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Interleukin Antagonists

Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system.

Why are interleukin antagonists prescribed?

  1. Plaque Psoriasis (22%)
  2. Psoriatic Arthritis (19%)
  3. Ulcerative Colitis (11%)
  4. Crohn's Disease (11%)
  5. Eczema (8%)
  6. Non-radiographic Axial Spondyloarthritis (8%)
  7. Ankylosing Spondylitis (8%)
  8. Prurigo Nodularis (3%)
  9. Juvenile Idiopathic Arthritis (3%)
  10. COVID-19 (3%)

Key takeaways

Interleukin antagonists are used to treat conditions such as rheumatoid arthritis, psoriasis, and asthma. They also have other uses, such as managing inflammatory bowel disease and COVID-19. These medications work by blocking the action of specific interleukins, which are proteins that can cause inflammation and other immune responses in your body. Interleukin antagonists typically come as injections and infusions. There are many examples available, including Stelara (ustekinumab), Bimzelx (bimekizumab), Nucala (mepolizumab), and more.

Prices for popular Interleukin Antagonists medications
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Bimzelx

as low as$5
BIMEKIZUMAB treats psoriasis. It works by slowing down an overactive immune system.  It is a monoclonal antibody.
Tremfya (guselkumab) is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. It is also used for the treatment of adults with active psoriatic arthritis. There are currently no generic alternatives for Tremfya. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.
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Ebglyss

as low as$3,362
Ebglyss is part of the Interleukin Antagonists class and treats Eczema. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Ebglyss is only available as a brand name drug.
Taltz (ixekizumab) is used to treat adults with psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, and for adults and children with moderate to severe plaque psoriasis. There are no generic alternatives to Taltz. It may be covered by Medicare or insurance plans.
Nemluvio is part of the Interleukin Antagonists class and treats Prurigo Nodularis and Eczema. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Nemluvio is only available as a brand name drug.
SECUKINUMAB treats autoimmune conditions, such as psoriasis and arthritis. It works by slowing down an overactive immune system. It is a monoclonal antibody.
Stelara (ustekinumab) is an expensive drug used to treat plaque psoriasis, psoriatic arthritis and ulcerative colitis. This medicine is also used to treat Crohn's disease. It is not a cure. This drug is more popular than comparable drugs. There are currently no generic alternatives to Stelara. While 96% of insurance plans cover the most common version of Stelara at a co-pay of $32.50-$80.00, many of them have restrictions.
TOCILIZUMAB treats autoimmune conditions, such as arthritis. It works by slowing down an overactive immune system. It may also be used to treat severe COVID-19 in people who are hospitalized. It is a monoclonal antibody.
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Tyenne

as low as$381
Tyenne is part of the Interleukin Antagonists class and treats Rheumatoid Arthritis. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Tyenne is only available as a brand name drug.
Yesintek is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Yesintek is only available as a brand name drug.
Pyzchiva is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Pyzchiva is only available as a brand name drug.
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Wezlana

as low as$2,670
Wezlana is part of the Interleukin Antagonists class and treats Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Wezlana is only available as a brand name drug.
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Adbry

as low as$3,899
TRALOKINUMAB reduces swelling, redness, itching, or rashes caused by skin conditions, such as eczema. It works by decreasing inflammation of the skin. It is a monoclonal antibody.
Steqeyma is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Steqeyma is only available as a brand name drug.
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Omvoh

as low as$10,436
MIRIKIZUMAB treats ulcerative colitis. It works by decreasing inflammation in the digestive tract. It is a monoclonal antibody.
Skyrizi (risankizumab-rzaa) is used to treat plaque psoriasis, psoriatic arthritis and crohn's disease. There are currently no generic alternatives for skyrizi. It may be covered by your Medicare or insurance plan.
Ustekinumab-ttwe (Pyzchiva) is part of the Interleukin Antagonists class and treats Plaque Psoriasis, Psoriatic Arthritis, Ulcerative Colitis and other conditions. Interleukin antagonists are used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, crohn's disease, psoriasis and other autoinflammatory syndromes. They work to reduce swelling and to suppress the immune system. Ustekinumab-ttwe (Pyzchiva) is only available as a brand name drug.
RILONACEPT treats inflammatory conditions, such as cryopyrin-associated perioidic syndromes (CAPS), deficiency of interluekin-1 receptor antagonist (DIRA), and pericarditis. It works by decreasing inflammation. This reduces symptoms.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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