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Compare Eucrisa vs. Hydrocortisone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Eucrisa (crisaborole)
    Topical hydrocortisone
  • Eucrisa (crisaborole)
    Topical hydrocortisone

  • Summary of Eucrisa vs. Hydrocortisone

    Summary for PDE4 inhibitor
    Prescription only

    Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

    Summary for Corticosteroid

    Topical hydrocortisone is a steroid medication used to treat different skin conditions, such as eczema. It's available in many different formulations, including cream, ointment, lotion, and solution. Some strengths are found over the counter (e.g., hydrocortisone 1%), while you need a prescription for others (e.g., hydrocortisone 2.5%). In general, most people experience few to no side effects while using topical hydrocortisone as directed. Rarely, topical hydrocortisone might cause topical steroid withdrawal (TSW). Watch out for skin rashes and irritations that get worse after stopping this medication.

  • Indications of Eucrisa vs. Hydrocortisone

    Indications for
    •Mild-to-moderate eczema
    Indications for

    Short-term relief of skin irritations (e.g., itching) due to:

    •Skin inflammation
    •Skin rashes
    •Eczema
    •Psoriasis
    •Insect bites
    •Poison ivy or oak
    •Skin allergies
    •Dry scalp
    •Genital or rectal irritation

  • Pros and Cons of Eucrisa vs. Hydrocortisone

    Pros and Const for PDE4 inhibitor
    Pros
    •Easy-to-apply ointment
    •Safe to use on children as young as 3 months old
    •Can start to see improvement in your skin in about 1 week
    •An alternative to topical steroids to treat eczema
    Cons
    •Must use twice daily
    •Can cause pain, burning, or stinging on the skin
    •Not approved for severe eczema
    •No lower-cost generic available
    Pros and Const for Corticosteroid
    Pros
    •Available as a lower-cost, generic medication
    •Available over the counter
    •Many formulations to choose from, such as ointment, cream, and solution
    Cons
    •Short-term use only, otherwise it might cause skin thinning and high blood sugar
    •Applied multiple times a day
    •Might affect your body's ability to fight off infections

  • Common Side Effects of Eucrisa vs. Hydrocortisone

    Common Side Effects for
    •Pain, burning, or stinging where the medication is applied (4%)
    Common Side Effects for
    •Burning
    •Itching
    •Skin irritation
    •Dry skin
    •Inflamed hair follicles

  • Warnings of Eucrisa vs. Hydrocortisone

    Common Side Effects for
    •Allergic reactions
    Common Side Effects for
    •Hormone problems and withdrawal
    •High blood sugar
    •New or worsened skin infection
    •Skin problems

  • Prices with our coupons for Eucrisa vs. Hydrocortisone

    Learn more about Eucrisa
    Learn more about Topical hydrocortisone

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