
Eucrisa
Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.
What is Eucrisa (crisaborole)?
What is Eucrisa (crisaborole) used for?
- Mild-to-moderate eczema
How Eucrisa (crisaborole) works
Eucrisa (crisaborole) is a phosphodiesterase 4 (PDE4) inhibitor. It blocks PDE4, a protein that plays a role in eczema and skin inflammation. By blocking PDE4, Eucrisa (crisaborole) is thought to lessen inflammation, itching, and redness to help treat eczema.
Drug facts
| Common Brands | Eucrisa |
|---|---|
| Drug Class | PDE4 inhibitor |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Eucrisa (crisaborole)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Pain, burning, or stinging where the medication is applied (4%)
Less Common Side Effects
- Itchy, red rash (hives)
Eucrisa (crisaborole) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: itchy red rash (hives); severe swelling of the skin; shortness of breath; chest tightness; swelling of the lips, tongue, or face
The following Eucrisa (crisaborole) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Burning, itching, crusting, or peeling of treated skin
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Mild skin irritation, redness, or dryness
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Pros and cons of Eucrisa (crisaborole)
Pros
- Easy-to-apply ointment
- Safe to use on children as young as 3 months old
- Can start to see improvement in your skin in about 1 week
- An alternative to topical steroids to treat eczema
Cons
- Must use twice daily
- Can cause pain, burning, or stinging on the skin
- Not approved for severe eczema
- No lower-cost generic available
Pharmacist tips for Eucrisa (crisaborole)
- Apply Eucrisa (crisaborole) on your skin only. Don't put it in or around your eyes, mouth, or vagina because this can lead to harmful side effects like serious irritation.
- Apply Eucrisa (crisaborole) onto the areas of eczema twice a day. Try to use the ointment around the same times each day and make it a part of your daily routine so you can easily remember to apply the medication.
- Since Eucrisa (crisaborole) can cause skin irritation, it might be helpful to use a small amount of the ointment on a small area of the skin as a test the first time you use the medication. This helps you figure out how your skin reacts to the medication before you use it regularly.
- Wash your hands well after you apply Eucrisa (crisaborole) onto the skin, unless you have hand eczema. If someone is helping you apply the medication, ask them to wash their hands properly after each time. Leftover ointment on your hands can accidentally get onto other places on the body and be irritating (e.g., rubbing your eyes with medication still on your fingers).
- There are several other things you can do to help your eczema from flaring. Use warm (not hot) water when you're showering or bathing. Also avoid using laundry detergent, cleaning products, and soaps that have preservatives, dyes, or fragrances because they can be too harsh.
- Store Eucrisa (crisaborole) at room temperature. Keep the tube tightly closed when you're not using it.
Risks and warnings for Eucrisa (crisaborole)
Eucrisa (crisaborole) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Allergic reactions
Some people have had allergic reactions, like hives, to Eucrisa (crisaborole). Stop using the medication right away if you have severe itching, swelling, or skin redness after you apply the ointment onto the skin. And call for emergency medical help as soon as possible if you have an itchy, red rash (hives) or shortness of breath. Discuss other treatment options with your prescriber if you're allergic or sensitive to Eucrisa (crisaborole).
Eucrisa (crisaborole) dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 60g of 2% | 1 tube | $158.48 | $158.48 |
| 100g of 2% | 1 tube | $223.14 | $223.14 |
Typical dosage for Eucrisa (crisaborole)
Apply a thin layer of the ointment twice daily on any areas of your skin that's affected by eczema. Once your skin improves, your prescriber might lower your dose to once a day.
How much does Eucrisa (crisaborole) cost?
$158.48
What are alternatives to Eucrisa (crisaborole)?
News about Eucrisa (crisaborole)
