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Eucrisa Coupon - Eucrisa 60g of 2% tube of ointment

Eucrisa

crisaborole
Used for Eczema
Used for Eczema

Eucrisa (crisaborole) is an ointment that's used to treat eczema for people 3 months and older. The medication is a phosphodiesterase 4 (PDE4) inhibitor that works to help reduce skin inflammation and itching from eczema. The ointment is usually applied to the affected area(s) of skin twice a day. The most common side effect is burning or stinging on the skin where you apply the medication.

Reviewed by:
reviewer
Shifali Patel, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on October 9, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesImagesReferencesPricesMedicare
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What is Eucrisa (crisaborole)?

What is Eucrisa (crisaborole) used for?

How Eucrisa (crisaborole) works

Eucrisa (crisaborole) is a phosphodiesterase 4 (PDE4) inhibitor. It blocks PDE4, a protein that plays a role in eczema and skin inflammation. By blocking PDE4, Eucrisa (crisaborole) is thought to lessen inflammation, itching, and redness to help treat eczema.

Drug Facts

Common BrandsEucrisa
Drug ClassPDE4 inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$939.84(save 20.38%)
GoodRx discount
$748.28
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What are the side effects of Eucrisa (crisaborole)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain, burning, or stinging where the medication is applied (4%)

Other Side Effects

  • Itchy, red rash (hives)

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Allergic reaction: itchy red rash (hives); severe swelling of the skin; shortness of breath; chest tightness; swelling of the lips, tongue, or face

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Mild skin irritation, redness, or dryness
pros-and-cons

Pros and cons of Eucrisa (crisaborole)

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Pros

Easy-to-apply ointment

Safe to use on children as young as 3 months old

Can start to see improvement in your skin in about 1 week

An alternative to topical steroids to treat eczema

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Cons

Must use twice daily

Can cause pain, burning, or stinging on the skin

Not approved for severe eczema

No lower-cost generic available

pharmacist-tips

Pharmacist tips for Eucrisa (crisaborole)

pharmacist

  • Apply Eucrisa (crisaborole) on your skin only. Don't put it in or around your eyes, mouth, or vagina because this can lead to harmful side effects like serious irritation.

    • Apply Eucrisa (crisaborole) onto the areas of eczema twice a day. Try to use the ointment around the same times each day and make it a part of your daily routine so you can easily remember to apply the medication.

      • Since Eucrisa (crisaborole) can cause skin irritation, it might be helpful to use a small amount of the ointment on a small area of the skin as a test the first time you use the medication. This helps you figure out how your skin reacts to the medication before you use it regularly.

        • Wash your hands well after you apply Eucrisa (crisaborole) onto the skin, unless you have hand eczema. If someone is helping you apply the medication, ask them to wash their hands properly after each time. Leftover ointment on your hands can accidentally get onto other places on the body and be irritating (e.g., rubbing your eyes with medication still on your fingers).

          • There are several other things you can do to help your eczema from flaring. Use warm (not hot) water when you're showering or bathing. Also avoid using laundry detergent, cleaning products, and soaps that have preservatives, dyes, or fragrances because they can be too harsh.

            • Store Eucrisa (crisaborole) at room temperature. Keep the tube tightly closed when you're not using it.

              faqs

              Frequently asked questions about Eucrisa (crisaborole)

              Is Eucrisa (crisaborole) a steroid?
              No, Eucrisa (crisaborole) isn't a steroid. Instead, it belongs to a group of medications called PDE4 inhibitors. Steroids and PDE4 inhibitors work differently. But they both reduce inflammation related to eczema to help with symptoms like redness and itching.
              Can you use Eucrisa (crisaborole) with hydrocortisone?
              Don't use any other medications with Eucrisa (crisaborole), including hydrocortisone, without asking your dermatologist or primary care provider first. There isn't much information about how safe using topical steroids like hydrocortisone together with Eucrisa (crisaborole) is or how well the combination works for eczema. Speak with your prescriber about your options if using Eucrisa (crisaborole) or hydrocortisone alone isn't enough to relieve your symptoms.
              Can Eucrisa (crisaborole) be used for psoriasis?
              Eucrisa (crisaborole) has been studied for psoriasis, but it isn't currently FDA approved for psoriasis. However, there are other medications in the same class that are approved for this skin condition. Talk to your dermatologist about the best treatment option for you.
              Can Eucrisa (crisaborole) be used on the face?
              Yes, you can apply Eucrisa (crisaborole) on your face if you have eczema there. Keep in mind that the areas of your face can be very sensitive and might get irritated from the medication more easily. Also try not to get Eucrisa (crisaborole) in or near your eyes, since this can cause irritation. If the medication gets in your eyes, flush them well with water.
              Can I buy Eucrisa (crisaborole) over the counter?
              No, Eucrisa (crisaborole) isn't available over the counter. You'll need a prescription from your healthcare professional.
              Does Eucrisa (crisaborole) expire?
              Yes, Eucrisa (crisaborole) expires. Check the expiration date on the tube of ointment, and don't use it if it's expired. Medications that have expired might not work as well anymore.
              How quickly does Eucrisa (crisaborole) work?
              In studies, some people saw improvements in their skin after 1 week of treatment. But most people didn't see clear or almost clear skin until after a few weeks of using Eucrisa (crisaborole). Don't be discouraged if you don't see improvement in your skin right away. Work with your dermatologist or primary care provider to create a treatment plan and use Eucrisa (crisaborole) exactly as prescribed. Discuss with your prescriber if you feel like the medication isn't working well for you.
              Can you use Eucrisa (crisaborole) while pregnant?
              Speak with your prescriber if you're pregnant or planning to become pregnant before you use Eucrisa (crisaborole). There isn't enough information to know whether this medication is safe to use while pregnant. So, it isn't known whether the medication can cause harm to your unborn baby. Discuss with your prescriber about the risks and benefits of using Eucrisa (crisaborole) during pregnancy.
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              What are the risks and warnings for Eucrisa (crisaborole)?

              Eucrisa (crisaborole) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Allergic reactions

              Some people have had allergic reactions, like hives, to Eucrisa (crisaborole). Stop using the medication right away if you have severe itching, swelling, or skin redness after you apply the ointment onto the skin. And call for emergency medical help as soon as possible if you have an itchy, red rash (hives) or shortness of breath. Discuss other treatment options with your prescriber if you're allergic or sensitive to Eucrisa (crisaborole).

              dosage

              Eucrisa (crisaborole) dosage forms

              The average cost for 1 tube of 60g of 2% of Eucrisa (crisaborole) is $748.28 with a free GoodRx coupon. This is 20.38% off the average retail price of $939.84.
              tube of ointment
              Tube of ointment
              DosageQuantityPrice as low asPrice per unit
              60g of 2%1 tube$748.28$748.28
              100g of 2%1 tube$1047.72$1047.72

              Typical dosing for Eucrisa (crisaborole)

              Apply a thin layer of the ointment twice daily on any areas of your skin that's affected by eczema. Once your skin improves, your prescriber might lower your dose to once a day.

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              How much does Eucrisa (crisaborole) cost?

              To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
              Eucrisa (brand)
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              alternatives

              What are alternatives to Eucrisa (crisaborole)?

              There are a number of medications that your doctor can prescribe in place of Eucrisa (crisaborole). Compare a few possible alternatives below.
              Eucrisa (crisaborole)
              Used for:
              $748.28 Lowest GoodRx priceView Prices
              Tacrolimus (Protopic)
              Used for:

              • Moderate-to-severe eczema in adults and children ages 2 years and older

              $40.00 Lowest GoodRx priceView Prices
              Pimecrolimus (Elidel)
              Used for:

              • Mild-to-moderate eczema in people ages 2 years and older

              $70.00 Lowest GoodRx priceView Prices
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              References

              Best studies we found

              AAAAI/ACAAI JTF Atopic Dermatitis Guideline Panel, et al. (2024). Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE– and Institute of Medicine–based recommendations. Annals of Allergy, Asthma, & Immunology.

              Bissonnette, R., et al. (2019). Crisaborole and atopic dermatitis skin biomarkers: An intrapatient randomized trial. Journal of Allergy and Clinical Immunology.

              Crowley, E. L., et al. (2023). Phosphodiesterase-4 Inhibition in the management of psoriasis. Pharmaceutics.

              View All References (3)

              Guttman-Yassky, E., et al. (2018). The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition. Experimental Dermatology.

              Pfizer Laboratories Div Pfizer Inc. (2024). Eucrisa- crisaborole ointment [package insert]. DailyMed.

              Schlessinger, J., et al. (2020). Safety, effectiveness, and pharmacokinetics of crisaborole in infants aged 3 to < 24 months with mild-to-moderate atopic dermatitis: A phase IV Open-label study (CrisADe CARE 1). American Journal of Clinical Dermatology.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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