Key takeaways:
While there is no cure for atopic dermatitis (eczema), several treatments are available. Eucrisa (crisaborole) is one topical ointment used to treat the condition in adults and children who are at least 3 months old.
Eucrisa is a brand-name medication used to treat mild-to-moderate eczema. The average retail price of one 60 g tube of 2% ointment is $943.18. There is no generic option available.
If you’re eligible, you may be able to reduce the cost of Eucrisa with a manufacturer copay savings card or through a patient assistance program. You may also be able to save money by using a GoodRx coupon.
Save on related medications
If you're among the estimated 10% of people in the U.S. who have atopic dermatitis (eczema), you likely have experienced dry, itchy, or flaky skin. Eczema is a chronic condition that can affect different parts of the body, including the hands, face, legs, and feet.
While there is no cure for eczema, there are different types of treatments that can help you manage the symptoms. Eucrisa (crisaborole) is a topical ointment used to treat mild-to-moderate eczema in adults and children 3 months of age and older. The prescription medication works by blocking overactive enzymes in the skin that cause inflammation.
How much does Eucrisa cost?
Eucrisa is a brand-name medication; there is no generic version available. Here's what you might expect to pay for 1 tube of Eucrisa 2% ointment.
Eucrisa form and quantity | Average retail price |
1 tube of ointment, 60 g | |
1 tube of ointment, 100 g |
What factors affect the cost of Eucrisa?
Insurance can help defray some of the cost of Eucrisa. But if you don't have insurance, what you’ll pay for the medication depends on several factors, including your:
Pharmacy: All pharmacies set their own retail prices.
Location: Medication costs vary in different parts of the country — and even in different parts of the same city.
Fill quantity: Larger quantities of a medication typically cost less per dose than smaller quantities.
Use: The amount of medication you apply at a time impacts the amount of ointment you need — and your costs.
Does insurance cover Eucrisa?
Some health insurance plans cover Eucrisa. For example, nearly all Medicaid plans and commercial plans not purchased through an Affordable Care Act (ACA) marketplace cover this medication.
If you have insurance, review your plan’s summary of benefits and coverage and formulary (list of covered medications) to determine whether Eucrisa is covered. If not, contact your plan provider and ask about your coverage options. You can also discuss alternative approaches with your prescriber or a pharmacist.
How different insurance plans cover Eucrisa
The following chart shows the likelihood of having coverage for Eucrisa with different types of insurance plans. It also shows the likelihood of having prior authorization and step therapy requirements.
A certain amount of enrollees in every category are required to get prior authorization or do step therapy to get coverage for Eucrisa.
Insurance type | Enrollees covered for Eucrisa 2% ointment | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
68.6% | 42.2% | 58.8% | |
Commercial plans (excluding ACA plans) | 94.8% | 22.3% | 73.7% |
Medicare, including original Medicare and Medicare Advantage plans | 8.3% | 7% | 4.4% |
Medicaid, including state-run and managed care plans | 99.8% | 85% | 53.9% |
Source: Managed Markets Insight & Technology, LLC™, as of June 13, 2025. (See methodology below.)
Tips if your medication isn’t covered by insurance
If your insurance doesn’t cover Eucrisa, you still have options. You can:
Use a GoodRx coupon, which may help you save on your prescription.
Ask your prescriber about less costly options that meet your needs. This could mean switching to another brand-name medication or to a generic medication.
Request a formulary exception from your insurance company. If your request is denied, you have the right to file an appeal with your plan.
Compare different health insurance plans when it’s time for open enrollment to find one that provides the coverage you need.
Living with eczema: Here’s what an extreme eczema flare-up feels like and how one woman got her symptoms under control.
Eczema and diet: What you eat can trigger your eczema, so it’s important to know what foods may activate an inflammatory response for you.
Over-the-counter treatments: You may be able to find relief from eczema without a prescription via antihistamines, moisturizers, or hydrocortisone creams.
Ways to save on Eucrisa
Without savings, Eucrisa may be a stretch for your budget. Whether or not you have insurance, there are ways to reduce the cost. Here are four options.
1. Use a GoodRx coupon
You may be able to use a free GoodRx coupon to lower the price of your Eucrisa prescription. For example, you could pay as low as $778.06 for one 60 g tube of Eucrisa 2% ointment with a GoodRx coupon at certain pharmacies. And you could pay as low as $1087.08 for one 100 g tube of Eucrisa 2% ointment.
Visit www.goodrx.com or the GoodRx app to download and use a coupon today. Here’s how:
On the app or website, type “Eucrisa” in the search field.
Choose the desired quantity. Input your ZIP code or address, or select “Use my current location,” so you see results for local pharmacies.
Choose how to receive your coupon. You may want it emailed or texted to you, or you may want to print it out.
Take your coupon with you to the pharmacy. You can also present the coupon to the pharmacy’s staff early in the filling process to avoid delays at the pickup counter.
2. See if you qualify for a copay savings card
Pfizer is the company that makes Eucrisa. Pfizer offers financial assistance for many of its medications, including Eucrisa.
With the Pfizer Dermatology Patient Access copay savings card, you may be able to reduce your copays to $10 if you have commercial insurance that covers Eucrisa, or $100 if your insurance does not cover the medication. The program has limits, though. You can save up to $970 per tube of Eucrisa and no more than $3,880 in a calendar year on the medication.
You can sign up for a copay card through the Pfizer Dermatology Patient Access registration portal.
3. Check if you’re eligible for a patient assistance program
If you don't have commercial insurance or any type of insurance, you may still qualify for assistance. If you are uninsured or have Medicare Part D and meet additional qualifications, you may be eligible for free Eucrisa through the Pfizer Patient Assistance Program.
You may also be able to find help through other patient assistance programs. If you have insurance, the Patient Access Network (PAN) Foundation has an atopic dermatitis (eczema) fund to help you cover copays and other costs. At the time of publication, this fund was not accepting new enrollees, but you can join the waitlist.
4. Tap into your HSA, FSA, or HRA
Consider using a flexible spending account (FSA), health savings account (HSA), or health reimbursement arrangement (HRA) to pay for your medication. These types of accounts have multiple tax benefits when they’re used to pay for qualified healthcare expenses. This can reduce your out-of-pocket costs through tax savings. But be sure to review your account’s contribution limits, rollover limits, and eligible expenses.
The bottom line
Eucrisa (crisaborole) is a topical ointment used to treat atopic dermatitis (eczema). What you’ll pay for Eucrisa depends on factors such as the pharmacy you use and your insurance coverage status. Without insurance, the average price of one 60 g tube of Eucrisa 2% ointment is $943.18. But you could pay as little as $778.06 with a GoodRx coupon at select pharmacies.
If you have commercial insurance, you may be able to take advantage of Pfizer's copay savings card, which could allow you to pay as little as $10 per tube. Or, if you qualify, you may be able to receive free Eucrisa through the Pfizer Patient Assistance Program or get help from a patient advocacy organization.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of June 2025.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
Allergy & Asthma Network. (n.d.). What if I can't afford my eczema medications?
Children’s National Hospital. (n.d.). Pediatric eczema (atopic dermatitis).
Guttman-Yassky, E., et al. (2018). The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition. Experimental Dermatology.
Medicaid.gov. (n.d.). Managed care.
National Eczema Association. (n.d.). Eczema stats.
National Eczema Association. (2025). Types of eczema.
Patient Access Network Foundation. (n.d.). Atopic dermatitis.
Pfizer Dermatology Patient Access. (n.d.). Eucrisa crisaborole ointment 2%.
Pfizer Dermatology Patient Access. (n.d.). Financial support.
Pfizer Dermatology Patient Access. (n.d.). Patient portal.
Pfizer Dermatology Patient Access. (2023). Pfizer Patient Assistance Program.
Pfizer Laboratories. (2025). Eucrisa - crisaborole ointment [package insert].
Pfizer RxPathways. (n.d.). Available medications.