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Compare Dupixent vs. Adbry

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dupixent (dupilumab) and Adbry (tralokinumab) are both biologic medications used to treat moderate-to-severe eczema. They work by targeting proteins in the immune system to reduce inflammation. However, they have some important differences. Dupixent is approved for a wider range of conditions, including asthma and sinus congestion with nasal polyps, whereas Adbry is specifically for eczema. Dupixent can be used in children as young as 6 months, while Adbry is only for those 12 years and older. Dupixent is typically injected every 1 to 4 weeks, while Adbry is injected every 2 to 4 weeks. Common side effects of Dupixent include injection site reactions and eye inflammation, while Adbry may cause upper respiratory infections and pink eye.

  • Dupixent (dupilumab)
    Adbry (tralokinumab)
  • Dupixent (dupilumab)
    Adbry (tralokinumab)

  • Summary of Dupixent vs. Adbry

    Summary for Interleukin antagonist
    Prescription only

    Dupixent (dupilumab) is an injection that helps treat certain inflammatory conditions. This includes eczema, asthma, and chronic obstructive pulmonary disease (COPD), among others. It's a biologic medication known as an interleukin antagonist that lowers inflammation. Dupixent (dupilumab) comes as prefilled pens and prefilled syringes. It's injected under the skin of the belly or thighs (or in the back of the upper arm with someone's help). The dosing schedule depends on the condition you have, your age, and your weight. It's injected either every week, every 2 weeks, or every 4 weeks. Side effects include injection site reactions and eye problems.

    Summary for Interleukin-13 (IL-13) antagonist
    Prescription only

    Adbry (tralokinumab or tralokinumab-ldrm) is a biologic medication called an interleukin antagonist. It's FDA approved to treat moderate-to-severe eczema in people 12 years and older. It's used when topical medications don't work well enough or can't be used. Adbry (tralokinumab) comes in prefilled syringes. Autoinjectors are also available for adults. You inject your dose under the skin once every 2 or 4 weeks. Side effects include upper respiratory tract infections and injection site reactions.

  • Indications of Dupixent vs. Adbry

    Indications for
    •Moderate-to-severe eczema - for people 6 months and older
    •Moderate-to-severe asthma - add-on maintenance for people 6 years and older
    •Long-term sinus congestion with nasal polyps - add-on maintenance for people 12 years and older
    •Eosinophilic esophagitis - for people 1 year and older
    •Prurigo nodularis (long-term itchy skin bumps) - for adults
    •Chronic obstructive pulmonary disease (COPD) - add-on maintenance for adults
    •Long-term hives - for people 12 years and older
    Indications for
    •Moderate-to-severe eczema in people ages 12 years and older

  • Pros and Cons of Dupixent vs. Adbry

    Pros and Const for Interleukin antagonist
    Pros
    •Taken every other week or monthly for most conditions
    •Approved for some children (specific age depends on the condition)
    •Available as prefilled pens (for people ages 2 years and older)
    •Available as prefilled syringes (for people ages 6 months and older)
    Cons
    •Given as an injection under the skin
    •Not used for helping with asthma attacks
    •Can cause injection reactions, such as pain, bruising, and swelling
    •Unknown if it's safe or works well while pregnant or breastfeeding
    Pros and Const for Interleukin-13 (IL-13) antagonist
    Pros
    •Given every 2 or 4 weeks
    •Available as prefilled syringes (and autoinjectors for adults) for easier administration
    •Can use with or without topical steroids
    •Can use with topical calcineurin inhibitors (on problem areas only)
    Cons
    •Must inject the medication under the skin
    •Might need to give more than one injection to get the full dose each time
    •Doesn't cure eczema
    •Not approved for children younger than 12 years old

  • Common Side Effects of Dupixent vs. Adbry

    Common Side Effects for
    •Injection site reaction (e.g., pain, swelling, bruising; 10%)
    •Eye redness or eye inflammation (10%)
    •Cold sores (4%)
    Common Side Effects for
    •Upper respiratory infections (24%)
    •Pink eye (8%)
    •Injection site reactions (pain, redness, swelling; 7%)

  • Warnings of Dupixent vs. Adbry

    Common Side Effects for
    •Allergic reactions
    •Eye inflammation
    •Other inflammation in the body
    •Risk of worsening of breathing problems in people with asthma or COPD
    •Risk of psoriasis
    •Joint pain and psoriatic arthritis
    •Unknown effect in people with parasitic worm infections
    •Interaction with vaccines
    Common Side Effects for
    •Serious allergic reactions
    •Eye infection or inflammation
    •Get parasitic worm infections treated
    •Caution when getting vaccines

  • Prices with our coupons for Dupixent vs. Adbry

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