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Compare Tremfya vs. Ilumya

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tremfya (guselkumab) and Ilumya (tildrakizumab) are both injectable medications used to treat moderate-to-severe plaque psoriasis, but they have some key differences. Tremfya is also approved for treating active psoriatic arthritis, while Ilumya is not. You can inject Tremfya yourself at home after proper training, but Ilumya must be administered by a healthcare provider. Tremfya is given every 8 weeks after the initial doses, whereas Ilumya is given every 3 months after the first two doses. Both medications can be expensive. Tremfya can take several months to show full effects, with improvements in psoriasis seen after about 4 months and in psoriatic arthritis after about 6 months. Ilumya tends to show improvement in psoriasis plaques after about 3 months, with continued clearing after 7 months. Both medications can raise the risk of infections and have similar side effects, such as upper respiratory infections.

  • Tremfya (guselkumab)
    Ilumya (tildrakizumab)
  • Tremfya (guselkumab)
    Ilumya (tildrakizumab)

  • Summary of Tremfya vs. Ilumya

    Summary for Interleukin antagonist
    Prescription only

    Tremfya (guselkumab) is an injection for adults with certain inflammatory conditions. It helps treat plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Tremfya (guselkumab) is a monoclonal antibody known as an interleukin antagonist. It calms your immune system to lower inflammation. The dosing schedule is every 1 or 2 months, depending on your condition and how far along you are in treatment. Side effects are upper respiratory infections, headache, and injection site reactions. There's also a risk of other infections and liver problems as long-term side effects.

    Summary for Interleukin-23 antagonist
    Prescription only

    Ilumya (tildrakizumab or tildrakizumab-asmn) is used to treat plaque psoriasis in adults. It's a type of monoclonal antibody called an interleukin-23 antagonist. It works by lowering inflammation in the skin. This medication is given as an injection under the skin every 3 months by a healthcare professional. Some people might have upper respiratory tract infections as a side effect. Ilumya (tildrakizumab) is only available as a brand-name medication.

  • Indications of Tremfya vs. Ilumya

    Indications for
    •Moderate-to-severe plaque psoriasis
    •Active psoriatic arthritis
    •Moderate-to-severe ulcerative colitis (UC)
    •Moderate-to-severe Crohn's disease (CD)
    Indications for
    •Moderate-to-severe plaque psoriasis

  • Pros and Cons of Tremfya vs. Ilumya

    Pros and Const for Interleukin antagonist
    Pros
    •An option for adults with plaque psoriasis who've already tried topical treatment
    •Given every 1 or 2 months (depending on your condition and treatment plan)
    •Few side effects
    •Can give yourself injections under the skin at home after you get trained
    Cons
    •Given as an injection under the skin or injection through the vein
    •Raises the risk of infections
    •Can cause some injection site reactions
    •Can take several months to see the benefits of the medication
    Pros and Const for Interleukin-23 antagonist
    Pros
    •Only given every 3 months, after the first two doses
    •Few side effects
    Cons
    •Needs to be injected by a healthcare professional, not on your own at home
    •Not approved for other skin problems or autoimmune conditions

  • Common Side Effects of Tremfya vs. Ilumya

    Common Side Effects for
    •Upper respiratory infections (14%)
    •Headache (5%)
    •Injection site reactions (5%)
    •Joint pain (3%)
    Common Side Effects for
    •Upper respiratory infections (14%)

  • Warnings of Tremfya vs. Ilumya

    Common Side Effects for
    •Serious allergic reactions
    •Risk of infections
    •Liver damage
    •Interaction with vaccines
    Common Side Effects for
    •Serious allergic reactions
    •Higher risk of infections
    •Avoid live vaccines

  • Prices with our coupons for Tremfya vs. Ilumya

    Learn more about Tremfya
    Learn more about Ilumya

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