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Compare Duobrii vs. Cosentyx

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Duobrii (halobetasol / tazarotene)
    Cosentyx (secukinumab)
  • Duobrii (halobetasol / tazarotene)
    Cosentyx (secukinumab)

  • Summary of Duobrii vs. Cosentyx

    Summary for Corticosteroid / Retinoid
    Prescription only

    Duobrii is a combination medication that contains halobetasol (a corticosteroid) and tazarotene (a retinoid). It's a prescription topical lotion that's FDA-approved to treat plaque psoriasis in adults. The directions for using the medication are to apply a thin amount over the affected area(s) of skin once per day. But avoid putting on the face, groin, and underarms. Side effects aren't common, but can include skin rash and pain at the site of application. Duobrii is brand name only and not available as a generic.

    Summary for Interleukin 17 (IL-17) inhibitor
    Prescription only

    Cosentyx (secukinumab) is a monoclonal antibody known as an interleukin 17 (IL-17) inhibitor. It's used to treat several inflammatory conditions, including plaque psoriasis, ankylosing spondylitis, and hidradenitis suppurativa. Cosentyx (secukinumab) comes as a pre-filled pen and syringe, and is typically injected under the skin monthly. It can also be given as an infusion through the veins by a healthcare provider for certain conditions, usually in a clinic setting. Side effects aren't common, but can include the common cold and diarrhea.

  • Indications of Duobrii vs. Cosentyx

    Indications for
    •Plaque psoriasis in adults
    Indications for
    •Plaque psoriasis (PsO) in people ages 6 years and older
    •Psoriatic arthritis (PsA) in people ages 2 years and older who weigh at least 33 lbs
    •Ankylosing spondylitis (AS) in adults
    •Non-radiographic axial spondyloarthritis (nr-axSpA) in adults
    •Enthesitis-related arthritis in people ages 4 years and older who weigh at least 33 lbs
    •Hidradenitis suppurativa in adults

  • Pros and Cons of Duobrii vs. Cosentyx

    Pros and Const for Corticosteroid / Retinoid
    Pros
    •Applied once daily
    •Combines two medications into one lotion
    •Might see some improvements in as early as 2 weeks
    Cons
    •For adults only; not studied in children
    •Not safe to use while pregnant or breastfeeding
    •Available as a brand-name product only
    Pros and Const for Interleukin 17 (IL-17) inhibitor
    Pros
    •Works well to treat several different inflammatory problems
    •Injected monthly (after the loading doses)
    •Available as a prefilled syringe or Sensoready pen for easy at-home injections
    •Can be used in children (for plaque psoriasis, psoriatic arthritis, and enthesitis-related arthritis)
    Cons
    •Only available as injections
    •Raises the risk of infections
    •Can worsen inflammatory bowel disease (IBD) (e.g., ulcerative colitis or Crohn's disease) symptoms
    •Pens and prefilled syringes not appropriate for those with latex allergy

  • Common Side Effects of Duobrii vs. Cosentyx

    Common Side Effects for
    •Skin rash (7%)
    •Pain where the medication was applied (3%)
    Common Side Effects for
    •Common cold (12%)
    •Diarrhea (4%)
    •Upper respiratory infections (3%)

    Note: Side effects listed were reported by adults who took Cosentyx (secukinumab) for PsO in clinical trials.

  • Warnings of Duobrii vs. Cosentyx

    Common Side Effects for
    •Harm to unborn babies
    •Altered stress hormone levels
    •Skin reactions and skin infections
    •Sun sensitivity and risk of sunburn
    •Cataracts and glaucoma
    Common Side Effects for
    •Infections
    •Caution when getting vaccines
    •Allergic and skin reactions
    •Worsening of inflammatory bowel disease

  • Prices with our coupons for Duobrii vs. Cosentyx

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    Learn more about Cosentyx

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