Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Skyrizi vs. Taltz

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Skyrizi (risankizumab)
    Taltz (ixekizumab)
  • Skyrizi (risankizumab)
    Taltz (ixekizumab)

  • Summary of Skyrizi vs. Taltz

    Summary for Interleukin antagonist
    Prescription only

    Skyrizi (risankizumab or risankizumab-rzaa) is an injection used to treat different inflammatory conditions in adults. This includes plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. It belongs to the drug class called interleukin antagonists. It works to lower inflammation and relieve symptoms. After the first few doses, you usually get the Skyrizi (risankizumab) injection every 2 or 3 months. This medication can raise your risk of infection as a side effect.

    Summary for Interleukin antagonist
    Prescription only

    Taltz (ixekizumab) is a monoclonal antibody known as an interleukin antagonist. It's used to treat inflammatory problems, including plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis. Taltz (ixekizumab) is available as a prefilled syringe and prefilled autoinjector. It's given as an injection under the skin once per month. Side effects include upper respiratory infections and injection-site reactions (e.g., pain, redness).

  • Indications of Skyrizi vs. Taltz

    Indications for
    •Moderate-to-severe plaque psoriasis in adults
    •Psoriatic arthritis in adults
    •Moderate-to-severe Crohn's disease in adults
    •Moderate-to-severe ulcerative colitis in adults
    Indications for
    •Moderate-to-severe plaque psoriasis in people ages 6 years and older
    •Psoriatic arthritis (PsA) in adults
    •Ankylosing spondylitis (AS) in adults
    •Non-radiographic axial spondyloarthritis (nr-axSpA) in adults

  • Pros and Cons of Skyrizi vs. Taltz

    Pros and Const for Interleukin antagonist
    Pros
    •Given every 2 or 3 months after a couple of starter doses (depends on your condition)
    •Can give injections under the skin at home after you get trained
    Cons
    •Must be given as an injection
    •Not approved for children
    Pros and Const for Interleukin antagonist
    Pros
    •Given once per month (after the first few doses)
    •Available as a prefilled syringe or autoinjector for easier use
    •Can inject at home after proper training
    Cons
    •Only given as an injection under the skin
    •Raises the risk of infections
    •Might cause flare ups in people with Crohn's disease or ulcerative colitis

  • Common Side Effects of Skyrizi vs. Taltz

    Common Side Effects for
    •Upper respiratory infections (13%)
    •Headache (4%)
    •Tiredness (3%)
    Common Side Effects for
    •Reaction at the injection site (e.g., redness, pain; 17%)
    •Upper respiratory infections (14%)

  • Warnings of Skyrizi vs. Taltz

    Common Side Effects for
    •Allergic reaction
    •Risk of infection
    •Rare case of liver injury
    •Caution when getting vaccines
    Common Side Effects for
    •Infections
    •Caution when getting vaccines
    •Allergic reaction
    •Inflammatory bowel disease

  • Prices with our coupons for Skyrizi vs. Taltz

    Learn more about Skyrizi
    Learn more about Taltz

Compare other Plaque Psoriasis and Psoriatic Arthritis drugs

Duobrii vs SkyriziEntyvio vs SkyriziOmvoh vs SkyriziRinvoq vs SkyriziSkyrizi vs BimzelxSkyrizi vs CosentyxSkyrizi vs DupixentSkyrizi vs EnbrelSkyrizi vs HumiraSkyrizi vs IlumyaSkyrizi vs OtezlaSkyrizi vs RemicadeSkyrizi vs SimponiSkyrizi vs TaltzSotyktu vs SkyriziStelara vs SkyriziTremfya vs SkyriziCimzia vs HumiraCosentyx vs HumiraEnbrel vs HumiraEntyvio vs HumiraHumira vs DovonexHumira vs PrednisoneHumira vs SimponiHumira vs TaclonexHumira vs TazoracHumira vs VanosOrencia vs HumiraOtezla vs HumiraRemicade vs Humira
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.