Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Entyvio vs. Entocort

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Entyvio (vedolizumab) and Entocort EC (budesonide) are both used to treat Crohn's disease, but they work in different ways and are used for different severities of the condition. Entyvio is a biologic medication known as an integrin antagonist, which is given either as an intravenous infusion or a subcutaneous injection. It is used for moderate-to-severe Crohn's disease and works by reducing the activity of immune cells to lower inflammation. On the other hand, Entocort EC is a corticosteroid taken orally and is used for mild-to-moderate Crohn's disease. It works by reducing inflammation directly in the intestines. Entyvio can cause serious side effects like infusion reactions and infections, while Entocort EC might lead to weight gain, infections, and other steroid-related side effects. Entocort EC is available as a lower-cost generic, whereas Entyvio does not have a generic form.

  • Entyvio (vedolizumab)
    Budesonide
  • Entyvio (vedolizumab)
    Budesonide

  • Summary of Entyvio vs. Entocort

    Summary for Integrin antagonist
    Prescription only

    Entyvio, the brand name for vedolizumab, is an injection used to treat ulcerative colitis (UC) and Crohn's disease (CD) in adults. It belongs to a drug class called integrin antagonists that helps lower inflammation in the gut. Entyvio (vedolizumab) is an infusion that's given through the vein by a healthcare professional. After the first 2 doses, it's usually given every 2 months. If it works well, people can switch to injections under the skin every 2 weeks using prefilled syringes or pens. Side effects include headache, mild infections, and joint pain.

    Summary for Corticosteroid
    Prescription only

    Budesonide is a corticosteroid that's used to treat mild-to-moderate Crohn's disease in adults and children. It's available as capsules that are taken by mouth once daily. The most common side effects are headache and respirator infections. More rarely, it might cause weight gain too.

  • Indications of Entyvio vs. Entocort

    Indications for
    •Moderate-to-severe ulcerative colitis (UC) in adults
    •Moderate-to-severe Crohn's disease (CD) in adults
    Indications for
    •Mild-to-moderate active Crohn's disease in people ages 8 years and older
    •Maintenance of remission of Crohn's disease in adults

  • Pros and Cons of Entyvio vs. Entocort

    Pros and Const for Integrin antagonist
    Pros
    •Have the option for infusions through the vein or injections under the skin after 6 weeks of treatment
    •Comes as prefilled syringes and pens for injections under the skin that can be given at home
    Cons
    •IV infusions can only be given by a healthcare professional at a medical office
    •Can raise your risk of serious side effects, like infusion reactions and infections
    Pros and Const for Corticosteroid
    Pros
    •Works where you have symptoms in your intestines (gut)
    •Might cause fewer side effects than other steroids
    •Taken once a day
    •Available as a lower-cost generic
    Cons
    •Not recommended for long-term use
    •Might not work as well as other steroids like prednisone
    •Can raise your risk for infections
    •Can take a couple months to see full benefit from the medication

  • Common Side Effects of Entyvio vs. Entocort

    Common Side Effects for
    •Infection in nose and throat (13%)
    •Headache (12%)
    •Joint pain (12%)
    •Nausea (9%)
    •Fever (9%)
    •Upper respiratory tract infection (7%)
    •Fatigue (6%)
    •Cough (5%)
    Common Side Effects for

    Treatment of active, mild-to-moderate Crohn’s disease:

    •Headache (21%)
    •Infection in your air passageway (respiratory infection; 11%)
    •Nausea (11%)
    •Back pain (7%)
    •Dizziness (7%)
    •Upset stomach or indigestion (6%)
    •Gas (6%)
    •Stomach pain (6%)
    •Vomiting (6%)
    •Feeling tired (5%)
    •Pain (5%)

    Maintenance of remission of Crohn’s disease**:

    •Diarrhea (10%)
    •Sinus inflammation (8%)
    •Viral infection (6%)
    •Joint pain (5%)

    ** Side effects listed are in addition to those observed with treatment of active Crohn's disease.

  • Warnings of Entyvio vs. Entocort

    Common Side Effects for
    •Infusion-related reactions and allergic reactions
    •Risk of serious infections
    •Risk of brain infection (progressive multifocal leukoencephalopathy)
    •Liver problems
    Common Side Effects for
    •Changes in stress hormone levels in the body
    •Higher risk of infections
    •Worsening of certain medical conditions

  • Prices with our coupons for Entyvio vs. Entocort

    Learn more about Entyvio
    Learn more about Budesonide

Compare other Crohn's Disease drugs

Entyvio vs HumiraEntyvio vs OrtikosEntyvio vs RinvoqEntyvio vs SkyriziEntyvio vs StelaraInflectra vs EntyvioRemicade vs EntyvioTremfya vs EntyvioZeposia vs EntyvioEticovo vs RinvoqOlumiant vs RinvoqOrencia vs RinvoqOrtikos vs AzasanOrtikos vs ImuranOrtikos vs RemicadeOrtikos vs StelaraOrtikos vs TrexallOrtikos vs TysabriRemicade vs RinvoqRinvoq vs ActemraRinvoq vs CibinqoRinvoq vs CimziaRinvoq vs CosentyxRinvoq vs DupixentRinvoq vs EnbrelRinvoq vs HumiraRinvoq vs OtezlaRinvoq vs SimponiRinvoq vs SkyriziRinvoq vs Xeljanz
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.