Compare Entyvio vs. Entocort
Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Entyvio (vedolizumab) and Entocort EC (budesonide) are both used to treat Crohn's disease, but they work in different ways and are used for different severities of the condition. Entyvio is a biologic medication known as an integrin antagonist, which is given either as an intravenous infusion or a subcutaneous injection. It is used for moderate-to-severe Crohn's disease and works by reducing the activity of immune cells to lower inflammation. On the other hand, Entocort EC is a corticosteroid taken orally and is used for mild-to-moderate Crohn's disease. It works by reducing inflammation directly in the intestines. Entyvio can cause serious side effects like infusion reactions and infections, while Entocort EC might lead to weight gain, infections, and other steroid-related side effects. Entocort EC is available as a lower-cost generic, whereas Entyvio does not have a generic form.
- Entyvio (vedolizumab)Budesonide
- Entyvio (vedolizumab)Budesonide
Summary of Entyvio vs. Entocort
Summary for Integrin antagonistPrescription onlyEntyvio (vedolizumab) is a monoclonal antibody known as an integrin antagonist. It's used to treat ulcerative colitis (UC) and Crohn's disease (CD) in adults. Entyvio (vedolizumab) is typically given as an infusion once every 2 months (after the starting doses) by a healthcare provider. People also have the option of getting this medication as an injection under the skin once every 2 weeks if the IV infusion worked well for them. Some of the more common side effects of Entyvio (vedolizumab) include headache, mild infections, and joint pain.
Summary for CorticosteroidPrescription onlyBudesonide is a corticosteroid that's used to treat mild-to-moderate Crohn's disease in adults and children. It's available as capsules that are taken by mouth once daily. The most common side effects are headache and respirator infections. More rarely, it might cause weight gain too.
Indications of Entyvio vs. Entocort
Indications for•Moderate-to-severe Crohn's disease (CD) in adults•Moderate-to-severe ulcerative colitis (UC) in adultsIndications for•Mild-to-moderate active Crohn's disease in people ages 8 years and older•Maintenance of remission of Crohn's disease in adultsPros and Cons of Entyvio vs. Entocort
Pros and Const for Integrin antagonistPros•Works well to treat UC and CD symptoms•Available as a prefilled syringe and pen that's given as an injection under the skin (SC) at home•Each IV infusion typically only takes 30 minutesCons•The IV infusion can only be given by a healthcare professional•The SC injection can be difficult for some people to administer•Can raise your risk for serious side effects, such as infusion reactions and infectionsPros and Const for CorticosteroidPros•Works where you have symptoms in your intestines (gut)•Might cause fewer side effects than other steroids•Taken once a day•Available as a lower-cost genericCons•Can raise your risk for infections•Can take a couple months to see full benefit from the medicationCommon Side Effects of Entyvio vs. Entocort
Common Side Effects for•Infection in nose and throat (13%)•Headache (12%)•Joint pain (12%)•Nausea (9%)•Fever (9%)•Upper respiratory tract infection (7%)•Fatigue (6%)•Cough (5%)Common Side Effects forTreatment of active, mild-to-moderate Crohn’s disease:
•Headache (21%)•Infection in your air passageway (respiratory infection; 11%)•Nausea (11%)•Back pain (7%)•Dizziness (7%)•Upset stomach or indigestion (6%)•Gas (6%)•Stomach pain (6%)•Vomiting (6%)•Feeling tired (5%)•Pain (5%)Maintenance of remission of Crohn’s disease**:
•Diarrhea (10%)•Sinus inflammation (8%)•Viral infection (6%)•Joint pain (5%)** Side effects listed are in addition to those observed with treatment of active Crohn's disease.
Warnings of Entyvio vs. Entocort
Common Side Effects for•Infusion-related reactions and allergic reactions•Serious infections•Brain infection (progressive multifocal leukoencephalopathy)•Liver problemsCommon Side Effects for•Changes in stress hormone levels in the body•Higher risk of infections•Worsening of certain medical conditionsPrices with our coupons for Entyvio vs. Entocort
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