Key takeaways
Entocort EC (budesonide) and Stelara (ustekinumab) are both used to treat Crohn's disease, but they have different uses and ways of working. Entocort EC is a corticosteroid taken by mouth once daily, while Stelara is an injectable medication given under the skin or through an IV. Entocort EC is specifically for mild-to-moderate Crohn's disease and works by reducing inflammation in the intestines. Stelara, on the other hand, treats a range of autoimmune conditions, including moderate-to-severe Crohn's disease, by blocking certain proteins in the immune system to lower inflammation. Entocort EC is available as a lower-cost generic, but Stelara does not have a generic form. Common side effects of Entocort EC include headaches and respiratory infections, while Stelara can cause nasal passage inflammation and headaches. Additionally, Stelara can weaken your immune system more significantly, raising the risk of infections and certain cancers.
