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Compare Remicade vs. Entyvio

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Infliximab (Remicade) and vedolizumab (Entyvio) are both disease-modifying antirheumatic drugs (DMARDs) used to treat autoimmune conditions like ulcerative colitis (UC) and Crohn's disease (CD). However, they have some important differences. Infliximab works by blocking tumor necrosis factor (TNF) to reduce inflammation. Vedolizumab, on the other hand, is an integrin antagonist that blocks proteins on immune cells to lower inflammation. Infliximab is administered as an intravenous (IV) infusion, while vedolizumab can be given either as an IV infusion or a subcutaneous injection. Infliximab is also used for conditions like rheumatoid arthritis and psoriasis, whereas vedolizumab is specifically for UC and CD in adults. Common side effects of infliximab include infections and infusion-related reactions, while vedolizumab may cause headaches and joint pain. Both medications can increase the risk of serious infections, but infliximab also has a risk of causing cancer and heart problems.

  • Remicade (infliximab)
    Entyvio (vedolizumab)
  • Remicade (infliximab)
    Entyvio (vedolizumab)

  • Summary of Remicade vs. Entyvio

    Summary for Biologic DMARD
    Prescription only

    Remicade (infliximab) is an injectable medication used to treat many autoimmune conditions, including ulcerative colitis and Crohn's disease. It's given through an intravenous (IV) infusion by a healthcare provider.

    Summary for Integrin antagonist
    Prescription only

    Entyvio, the brand name for vedolizumab, is an injection used to treat ulcerative colitis (UC) and Crohn's disease (CD) in adults. It belongs to a drug class called integrin antagonists that helps lower inflammation in the gut. Entyvio (vedolizumab) is an infusion that's given through the vein by a healthcare professional. After the first 2 doses, it's usually given every 2 months. If it works well, people can switch to injections under the skin every 2 weeks using prefilled syringes or pens. Side effects include headache, mild infections, and joint pain.

  • Indications of Remicade vs. Entyvio

    Indications for
    •Moderate-to-severe Crohn's disease (CD)
    •Moderate-to-severe ulcerative colitis (UC)
    •Moderate-to-severe rheumatoid arthritis (RA)
    •Ankylosing spondylitis (AS)
    •Psoriatic arthritis (PsA)
    •Severe plaque psoriasis (PsO)
    Indications for
    •Moderate-to-severe ulcerative colitis (UC) in adults
    •Moderate-to-severe Crohn's disease (CD) in adults

  • Pros and Cons of Remicade vs. Entyvio

    Pros and Const for Biologic DMARD
    Pros
    •Can be used for many autoimmune conditions
    •Typically only needs to be given every 6 to 8 weeks
    •Can be used in children 6 years of age and older for UC and CD
    Cons
    •Can only be given as an IV infusion by a healthcare professional
    •Can cause a lot of side effects
    •Brand name only, which can be expensive
    Pros and Const for Integrin antagonist
    Pros
    •Have the option for infusions through the vein or injections under the skin after 6 weeks of treatment
    •Comes as prefilled syringes and pens for injections under the skin that can be given at home
    Cons
    •IV infusions can only be given by a healthcare professional at a medical office
    •Can raise your risk of serious side effects, like infusion reactions and infections

  • Common Side Effects of Remicade vs. Entyvio

    Common Side Effects for
    •Infections
    •Nausea
    •Infusion-related reactions (e.g., headache, flushing, shortness of breath, rash)
    •Headache
    •Diarrhea
    •Stomach pain
    •Sore throat
    •Cough
    •Rash
    •Bronchitis
    •Indigestion
    •Tiredness
    •General pain
    •Joint pain
    Common Side Effects for
    •Infection in nose and throat (13%)
    •Headache (12%)
    •Joint pain (12%)
    •Nausea (9%)
    •Fever (9%)
    •Upper respiratory tract infection (7%)
    •Fatigue (6%)
    •Cough (5%)

  • Warnings of Remicade vs. Entyvio

    Common Side Effects for
    •Serious or deadly infections
    •Cancer
    •Liver problems and liver failure
    •Heart problems
    •Low blood cell counts
    •Nervous system problems
    •Medications to avoid
    Common Side Effects for
    •Infusion-related reactions and allergic reactions
    •Risk of serious infections
    •Risk of brain infection (progressive multifocal leukoencephalopathy)
    •Liver problems

  • Prices with our coupons for Remicade vs. Entyvio

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