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Prednisone vs. Allopurinol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Prednisone (Rayos, Prednisone Intensol) and allopurinol (Zyloprim) are both prescription medications, but they treat different conditions and belong to different drug classes. Prednisone is a corticosteroid used to manage an overactive immune system or inflammation, including autoimmune conditions and certain skin conditions. It works by calming the immune system. On the other hand, allopurinol is a xanthine oxidase inhibitor that lowers uric acid levels to treat gout, prevent kidney stones, and manage tumor lysis syndrome in cancer patients. Prednisone is available in various forms, including tablets and oral solutions, while allopurinol is only available as a tablet. Common side effects of prednisone include stomach irritation and mood changes, whereas allopurinol can cause diarrhea and nausea. Additionally, prednisone can lead to long-term issues like weight gain and weakened bones, while allopurinol may increase the risk of gout attacks when you first start taking it. Both medications require careful monitoring by your healthcare team to manage side effects and ensure they are working effectively.

Prices with our coupons for Prednisone vs. Allopurinol

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Prednisone10 tablets / 20mg
$8.85-
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Allopurinol30 tablets / 100mg
$9.39$9.47
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