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Compare Mannitol vs. Dexamethasone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bronchitol (mannitol) and dexamethasone are both prescription medications, but they serve different purposes and belong to different drug classes. Bronchitol (mannitol) is a mucolytic agent used to improve lung function in adults with cystic fibrosis (CF) by thinning mucus, making it easier to cough out. It is inhaled twice a day using a special inhaler. On the other hand, dexamethasone is a corticosteroid that treats a wide range of inflammatory conditions, including allergies, autoimmune diseases, and certain cancers. It can be taken orally or via injection. Unlike Bronchitol, dexamethasone has a generic form and is known for its long-lasting effects. While Bronchitol requires a tolerance test before use due to the risk of bronchospasm, dexamethasone has a broader range of side effects, including weight gain and weakened bones, especially with long-term use. Additionally, dexamethasone interacts with many other medications, so you need to inform your healthcare provider about all the drugs you are taking.

  • Bronchitol (mannitol)
    Dexamethasone
  • Bronchitol (mannitol)
    Dexamethasone

  • Summary of Mannitol vs. Dexamethasone

    Summary for Mucolytic agent
    Prescription only

    Bronchitol (mannitol) is a newly approved medication to improve lung function for adults with cystic fibrosis (CF). You'll need to inhale the medication twice a day, once in the morning and once in the evening. And you're only able to use Bronchitol (mannitol) if you can pass a test to determine whether you can tolerate the medication.

    Summary for Corticosteroid
    Prescription only

    Dexamethasone is a corticosteroid that's used to treat many inflammatory conditions, including allergic reactions and certain autoimmune conditions. If you've been taking dexamethasone for a long time, you're at higher risk for side effects like weight gain and weakened bones. Dexamethasone also has many drug interactions, so make sure to tell your provider and pharmacist what medications you're taking before starting this steroid. This medication is available as oral tablets and solutions, as well as an injection that's usually given in a healthcare setting.

  • Indications of Mannitol vs. Dexamethasone

    Indications for
    •Add-on treatment to improve lung function in adults with cystic fibrosis (CF)
    Indications for
    •Allergies and allergic reactions
    •Skin conditions
    •Hormone-related conditions
    •Eye conditions
    •Stomach conditions
    •Respiratory disorders
    •Autoimmune and rheumatic conditions
    •Multiple myeloma (Hemady brand only), blood cancers, and other blood-related conditions
    •Certain eye conditions
    •Nervous system and brain conditions
    •Kidney diseases
    •Shock

  • Pros and Cons of Mannitol vs. Dexamethasone

    Pros and Const for Mucolytic agent
    Pros
    •Works well to improve lung function
    •All components, including the capsules, are stored at room temperature
    •Inhaler is a small hand-held device that's convenient for travel
    Cons
    •Might be tricky to handle 10 capsules per dose twice a day
    •Available as a brand-name medication only, which can be expensive
    •Need to use a short-acting bronchodilator before using the medication to prevent bronchospasm
    Pros and Const for Corticosteroid
    Pros
    •Can treat many conditions
    •Works quickly to relieve symptoms and problems caused by an overactive immune system, like swelling or rash
    •Option to take it by mouth
    •Available as a liquid for children or people who can't take tablets by mouth
    Cons
    •Can cause trouble sleeping and headaches
    •Long-term use can cause problems with skin, bone, eye health and put you at a higher risk for infections
    •Can cause withdrawal symptoms if you stop taking too suddenly
    •Safety during pregnancy or breastfeeding isn't clear

  • Common Side Effects of Mannitol vs. Dexamethasone

    Common Side Effects for
    •Cough (15%)
    •Coughing up blood (10%)
    •Pain in mouth or throat (7%)
    Common Side Effects for
    •Difficulty sleeping
    •Higher blood sugar levels
    •Headache
    •Mood swings
    •Nausea
    •Stomach pain
    •Feeling more hungry
    •Weight gain

  • Warnings of Mannitol vs. Dexamethasone

    Common Side Effects for
    •Bronchospasm (narrowing of the airways)
    •Coughing up blood
    Common Side Effects for
    •Lowered stress hormone levels
    •Higher risk of infections
    •High blood pressure and kidney-related problems
    •Stomach and intestinal problems
    •Weakened bones
    •Eye problems

  • Prices with our coupons for Mannitol vs. Dexamethasone

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    Learn more about Dexamethasone

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