Compare Prednisone vs. Prednisolone
Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Prednisone and methylprednisolone are both corticosteroids used to treat conditions related to an overactive immune system or inflammation. Prednisone, available under brand names like Rayos and Prednisone Intensol, is taken orally and comes in immediate-release tablets, delayed-release tablets, and an oral liquid. Methylprednisolone, known by brands such as Depo-Medrol, Medrol, and Solu-Medrol, can be taken orally or as an injection. One key difference is that Methylprednisolone is available as an injection, which can be administered in a hospital or at home by a nurse. Both medications can cause similar side effects like weight gain, mood changes, and sleep problems, but Methylprednisolone is also known to cause skin thinning and blurry vision. Additionally, while both medications require a prescription, they are available in lower-cost generic forms. It's important to follow your healthcare provider's instructions closely when taking either medication to avoid withdrawal symptoms and other risks.
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Summary of Prednisone vs. Prednisolone
Prednisone is an oral corticosteroid. It's taken by mouth by adults and children to treat health conditions related to an overactive immune system or inflammation, such as allergies and certain skin conditions. Your healthcare team will determine your dose based on what medical condition you have. Some of the common short-term side effects of prednisone include stomach irritation and mood changes. And if you take this medication for a month or longer, you're more likely to experience long-term side effects, like weight gain and weakened immune system.
Oral prednisolone is a corticosteroid. It's taken by mouth to treat health conditions related to an overactive immune system or inflammation, such as rheumatoid arthritis and lupus, in adults and children. Your healthcare team will determine your dose based on what medical condition you have. Some common short-term side effects of prednisolone include trouble sleeping and mood changes. And if you take this medication for a longer period of time, you're more likely to experience long-term side effects, like weight gain and weakened immune system. If you need to stop prednisolone, your healthcare team might need to taper down your dosage slowly to avoid withdrawal symptoms.
Indications of Prednisone vs. Prednisolone
This medication is used for many different conditions. Generally, it's used for autoimmune problems, conditions related to swelling, or cancer. Some examples include:
This medication is used for many different conditions. Generally, it's used for autoimmune disorders, conditions related to swelling, or cancer. Some examples include:
Pros and Cons of Prednisone vs. Prednisolone
Common Side Effects of Prednisone vs. Prednisolone
Warnings of Prednisone vs. Prednisolone
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