Humira vs. Taltz for Plaque Psoriasis and Ankylosing Spondylitis: Important Differences and Potential Risks.

Humira

(adalimumab)

Taltz

(ixekizumab)

Summary for Humira

Prescription only

Humira (adalimumab) is an injection used to treat many different autoimmune conditions like rheumatoid arthritis, Crohn's disease, ulcerative colitis, and plaque psoriasis. As a TNF blocker, the medication works by blocking a protein that causes inflammation in your body. It's given as a shot under the skin once every 1 to 2 weeks, depending on your condition. Humira (adalimumab) doesn't have a true generic, but there are several similar versions called biosimilars. Common side effects include infections, injection site reactions, and headache.

Indications for Humira

Rheumatoid arthritis (RA) - adults only
Juvenile idiopathic arthritis (JIA) - people age 2 and older
Psoriatic arthritis (PsA) - adults only
Ankylosing spondylitis (AS) - adults only
Crohn's disease (CD) - people age 6 and older
Ulcerative colitis (UC) - people age 5 and older
Plaque psoriasis - adults only
Hidradenitis suppurativa (HS) - people age 12 and older
Uveitis - people age 2 and older

Pros and Cons for Humira

Pros

Can be used for many autoimmune conditions
Available as a ready-to-use pen that makes it easier to self-inject at home
Can be used in young children (as young as 2 years old for some conditions)
Only needs to be injected a couple times a month
Can be left at room temperature for up to 14 days if needed

Cons

Raises the risk of serious infections
Can take a few weeks or longer to work
Might be difficult to inject for some people
Can't receive any live vaccines while taking the medication
Might contain rubber or latex, which can cause a reaction for those with an allergy

Common Side Effects for Humira

Injection-site reaction (20%)
Upper respiratory tract infection (17%)
Headache (12%)
Rash (12%)
Sinus inflammation (11%)
Accidental injury (10%)
Nausea (9%)
Urinary tract infection (UTI) or bladder infection (8%)

Note: The side effects listed above were reported by adults with rheumatoid arthritis and are similar to those seen in people using Humira (adalimumab) for other conditions.

Warnings for Humira

Serious infections
Cancers
Severe allergic reactions
Nervous system effects
Low blood cell counts
Heart failure
Lupus-like syndrome
Live vaccines

Summary for Taltz

Prescription only

Taltz (ixekizumab) is an injection that's given under the skin. It helps treat inflammatory conditions, including plaque psoriasis, psoriatic arthritis, and some types of arthritis in the spine. This medication works as an interleukin antagonist to lessen inflammation in the body. You inject Taltz (ixekizumab) once a month using the prefilled syringe or autoinjector. The dose depends on the health problem you're treating. Side effects include upper respiratory infections. You also might feel pain or have redness around the injection area. Taltz (ixekizumab) is a brand-name medication.

Indications for Taltz

Moderate-to-severe plaque psoriasis in people 6 years and older
Psoriatic arthritis in adults
Ankylosing spondylitis in adults
Non-radiographic axial spondyloarthritis in adults

Pros and Cons for Taltz

Pros

Generally given once a month (might need some starter doses)
Available as a prefilled syringe or autoinjector for easier use
Can inject at home after a healthcare professional trains you (for most people)

Cons

Only given as an injection under the skin
Raises the risk of infections
Might cause flare-ups in people with Crohn's disease or ulcerative colitis

Common Side Effects for Taltz

Reaction at the injection site (e.g., redness, pain; 17%)
Upper respiratory tract infections (14%)

Warnings for Taltz

Risk of infection
Caution when getting vaccines
Eczema-like skin reaction
Allergic reaction
Inflammatory bowel disease

Prices with our coupons for Humira vs. Taltz

Humira1 carton / 2 pens of 40mg/0.4ml

$6,380.16$8,531.39

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Taltz1 carton / 1 autoinjector of 80mg/ml

$8,151.56-

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Humira vs. Taltz

Humira

Taltz

Summary for Humira

Indications for Humira

Pros and Cons for Humira

Pros

Cons

Common Side Effects for Humira

Warnings for Humira

Summary for Taltz

Indications for Taltz

Pros and Cons for Taltz

Pros

Cons

Common Side Effects for Taltz

Warnings for Taltz

Prices with our coupons for Humira vs. Taltz

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Humira

Taltz

Summary for Humira

Indications for Humira

Pros and Cons for Humira

Pros

Cons

Common Side Effects for Humira

Warnings for Humira

Summary for Taltz

Indications for Taltz

Pros and Cons for Taltz

Pros

Cons

Common Side Effects for Taltz

Warnings for Taltz