Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Humira (adalimumab) and fluocinonide (Vanos) are both prescription medications, but they are used for different purposes and come in different forms. Humira is an injectable biologic Disease Modifying Anti-Rheumatic Drug (DMARD) used to treat various autoimmune conditions like rheumatoid arthritis, Crohn's disease, and plaque psoriasis. It works by blocking a protein called tumor necrosis factor (TNF) to reduce inflammation. On the other hand, fluocinonide is a strong topical corticosteroid used to treat skin inflammation disorders such as psoriasis and eczema. It reduces inflammation and calms the immune system when applied to the skin. Humira is typically injected every other week, while fluocinonide is applied to the skin up to four times a day, depending on the strength. Humira can be used in children as young as 2 years old for some conditions, whereas the higher strength of fluocinonide should not be used in children under 12. Additionally, Humira has a higher risk of serious infections and certain cancers, while fluocinonide can cause skin reactions and hormonal changes if used for long periods.
Humira (adalimumab)
Fluocinonide (Vanos)
Humira (adalimumab)
Fluocinonide (Vanos)
Summary of Humira vs. Vanos
Summary for Biologic DMARD
Prescription only
Humira (adalimumab) is an injectable medication used for treating many different autoimmune conditions, including rheumatoid arthritis (RA), Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis. It's usually given every other week, and it can be used alone or taken with methotrexate or other non-biologic medications. This medication is available as many different brands (or biosimilars).
Summary for Corticosteroid
Prescription only
Fluocinonide (Vanos) is a strong topical steroid that treats skin inflammation and irritation, but it's not meant for long-term use. The medication comes in many different forms, such as a cream, ointment, gel, and topical solution.
Indications of Humira vs. Vanos
Indications for
•Rheumatoid arthritis (RA) - adults only
•Juvenile idiopathic arthritis (JIA) - people age 2 and older