Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Omvoh vs. Stelara

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Omvoh (mirikizumab)
    Stelara (ustekinumab)
  • Omvoh (mirikizumab)
    Stelara (ustekinumab)

  • Summary of Omvoh vs. Stelara

    Summary for Interleukin-23 antagonist
    Prescription only

    Omvoh (mirikizumab or mirikizumab-mrkz) helps treat ulcerative colitis and Crohn's disease in adults. It's a biologic known as an interleukin-23 antagonist. It works to help lower inflammation in the gut. When you first start, you'll get your first three doses as an infusion through the vein (IV) once a month at a clinic. After that, you (or your caregiver) can inject the rest of your doses under the skin every month at home. Side effects include joint pain and upper respiratory tract infections. Omvoh (mirikizumab) is available as a brand-name medication only.

    Summary for IL-12 and IL-23 antagonist
    Prescription only

    Stelara (ustekinumab) is an injectable medication used to treat autoimmune conditions like plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. As an interleukin antagonist, it works by blocking certain proteins that cause inflammation in your body, which helps reduce swelling and ease symptoms. You typically get it as an injection under your skin. Common side effects include common cold symptoms, headache, and feeling tired. This medication also has many biosimilars available.

  • Indications of Omvoh vs. Stelara

    Indications for
    •Moderate-to-severe ulcerative colitis in adults
    •Moderate-to-severe Crohn's disease in adults
    Indications for
    •Moderate-to-severe plaque psoriasis (Ps) - adults and children 6 years and older
    •Psoriatic arthritis (PsA) - adults and children 6 years and older
    •Moderate-to-severe Crohn's disease (CD) - adults only
    •Moderate-to-severe ulcerative colitis (UC) - adults only

  • Pros and Cons of Omvoh vs. Stelara

    Pros and Const for Interleukin-23 antagonist
    Pros
    •Given once a month
    •Available as ready-to-inject prefilled pens after the first three infusions
    •Can inject maintenance doses at home with proper training
    •Can improve symptoms when other treatments haven't worked well
    Cons
    •Injection only
    •Must get the first few doses as IV infusions from a healthcare professional
    •Must give two under-the-skin injections each time for a full maintenance dose
    •Risk of getting sick more easily
    Pros and Const for IL-12 and IL-23 antagonist
    Pros
    •After the first few doses, only need a shot every 8 to 12 weeks
    •Available as a prefilled syringe or vial
    •Syringes can be stored at room temperature for up to 30 days
    •Approved for children as young as 6 years old
    Cons
    •Can weaken your immune system and raise your risk of infection
    •Potential to cause serious allergic reactions
    •For CD and UC, the first dose must be given as an IV infusion
    •Can't receive live vaccines while taking this medication

  • Common Side Effects of Omvoh vs. Stelara

    Common Side Effects for

    Induction with IV infusions

    •Upper respiratory tract infections (8%)
    •Joint pain (2%)

    Maintenance with under-the-skin injections

    •Upper respiratory tract infections (14%)
    •Injection site reaction (e.g., redness, pain; 9%)
    •Joint pain (7%)
    Common Side Effects for

    Plaque psoriasis

    •Common cold symptoms (7-8%)
    •Upper respiratory tract infection (4-5%)
    •Headache (5%)

    Psoriatic arthritis

    •Joint pain (3%)
    •Nausea (3%)

    Crohn's disease

    •Common cold symptoms (11%)
    •Redness at the injection site (5%)
    •Yeast infection (5%)
    •Bronchitis (5%)

    Ulcerative colitis:

    •Common cold symptoms (24%)
    •Headache (10%)
    •Stomach pain (7%)
    •Flu infection (6%)
    •Fever (5%)

  • Warnings of Omvoh vs. Stelara

    Common Side Effects for
    •Allergic reactions
    •Risk of infection
    •Liver injury
    •Avoid live vaccines
    Common Side Effects for
    •Infections
    •Cancers
    •Severe allergic reaction
    •Brain condition
    •Vaccines
    •Lung problems

  • Prices with our coupons for Omvoh vs. Stelara

    Learn more about Omvoh
    Learn more about Stelara

Compare other Ulcerative Colitis and Crohn's Disease drugs

Omvoh vs SkyriziOmvoh vs StelaraDuobrii vs SkyriziEntyvio vs RinvoqEntyvio vs SkyriziEntyvio vs StelaraEticovo vs RinvoqOlumiant vs RinvoqOrencia vs RinvoqOrtikos vs StelaraRemicade vs RinvoqRinvoq vs ActemraRinvoq vs CibinqoRinvoq vs CimziaRinvoq vs SkyriziSkyrizi vs BimzelxSkyrizi vs CosentyxSkyrizi vs DupixentSkyrizi vs EnbrelSkyrizi vs HumiraSkyrizi vs IlumyaSkyrizi vs OtezlaSkyrizi vs RemicadeSkyrizi vs SimponiSkyrizi vs TaltzSotyktu vs SkyriziStelara vs RinvoqStelara vs SkyriziTremfya vs SkyriziTremfya vs Stelara
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.