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Compare Omvoh vs. Skyrizi

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Omvoh (mirikizumab)
    Skyrizi (risankizumab)
  • Omvoh (mirikizumab)
    Skyrizi (risankizumab)

  • Summary of Omvoh vs. Skyrizi

    Summary for Interleukin-23 antagonist
    Prescription only

    Omvoh (mirikizumab or mirikizumab-mrkz) is a biologic medication used to treat moderate-to-severe ulcerative colitis in adults. It helps reduce inflammation in the gut and colon. Typically, Omvoh (mirikizumab) is used when other options haven’t worked well. When you first start treatment, a healthcare professional will give you the first 3 doses as monthly intravenous (IV) infusions at a clinic, infusion center, or hospital. Then, you (or your caregiver) will get trained to inject the rest of your doses under the skin every month at home. Common side effects include joint pain and infections in the upper respiratory system (runny nose, sore throat).

    Summary for Interleukin antagonist
    Prescription only

    Skyrizi (risankizumab or risankizumab-rzaa) is an injection used to treat different inflammatory conditions in adults. This includes plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. It belongs to the drug class called interleukin antagonists. It works to lower inflammation and relieve symptoms. After the first few doses, you usually get the Skyrizi (risankizumab) injection every 2 or 3 months. This medication can raise your risk of infection as a side effect.

  • Indications of Omvoh vs. Skyrizi

    Indications for
    •Moderate-to-severe active ulcerative colitis in adults
    Indications for
    •Moderate-to-severe plaque psoriasis in adults
    •Psoriatic arthritis in adults
    •Moderate-to-severe Crohn's disease in adults
    •Moderate-to-severe ulcerative colitis in adults

  • Pros and Cons of Omvoh vs. Skyrizi

    Pros and Const for Interleukin-23 antagonist
    Pros
    •Given once every month
    •Available as ready-to-inject prefilled pens after first three infusions are completed
    •Can inject maintenance doses at home with proper training
    •Can improve symptoms when standard treatments don’t work
    Cons
    •Injection only
    •Must get the first few doses as IV infusions from a healthcare professional, likely at an infusion center or medical office
    •Must give two under-the-skin injections each time for a full maintenance dose
    •May be difficult to self-inject for those with hearing or vision problems, or those who have a hard time using their hands
    Pros and Const for Interleukin antagonist
    Pros
    •Given every 2 or 3 months after a couple of starter doses (depends on your condition)
    •Can give injections under the skin at home after you get trained
    Cons
    •Must be given as an injection
    •Not approved for children

  • Common Side Effects of Omvoh vs. Skyrizi

    Common Side Effects for

    Induction with IV infusions:

    •Upper respiratory tract infections (8%)
    •Joint pain (2%)

    Maintenance with under-the-skin injections:

    •Upper respiratory tract infections (14%)
    •Injection site reaction (e.g., redness, pain; 9%)
    •Joint pain (7%)
    Common Side Effects for
    •Upper respiratory infections (13%)
    •Headache (4%)
    •Tiredness (3%)

  • Warnings of Omvoh vs. Skyrizi

    Common Side Effects for
    •Allergic reactions
    •Infection risk
    •Liver injury
    •Avoid live vaccines
    Common Side Effects for
    •Allergic reaction
    •Risk of infection
    •Rare case of liver injury
    •Caution when getting vaccines

  • Prices with our coupons for Omvoh vs. Skyrizi

    Learn more about Omvoh
    Learn more about Skyrizi

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