Compare Humira vs. Prednisone

Humira (adalimumab) and prednisone are both used to treat conditions related to an overactive immune system, but they work in different ways and are used for different types of conditions. Humira is a biologic Disease Modifying Anti-Rheumatic Drugs (DMARD) that is injected under the skin and works by blocking a protein called Tumor Necrosis Factor (TNF) to reduce inflammation. It is used for autoimmune conditions like rheumatoid arthritis, Crohn's disease, and plaque psoriasis. Prednisone, on the other hand, is an oral corticosteroid that mimics a natural hormone in your body to calm down the immune response. It is used for a wide range of conditions, including allergies, skin conditions, and certain cancers. Humira is typically injected every other week, while prednisone is taken daily by mouth for a short term or longer term for certain chronic conditions. Humira can raise the risk of serious infections and certain cancers, while prednisone can cause side effects like mood changes, weight gain, and weakened bones if used long-term. Both medications require careful monitoring by your healthcare team to manage side effects and ensure they are working effectively.