Skip to main content
Drug bottle and Pill

Compare Diprolene vs. Vanos

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Betamethasone (Diprolene) and fluocinonide (Vanos) are both strong topical corticosteroids used to treat skin inflammation and itching. Betamethasone comes in various forms, including creams, ointments, gels, lotions, sprays, and foams, while fluocinonide is available as a cream, ointment, gel, and topical solution. Betamethasone can be used for up to 2 weeks for most formulations, but the Sernivo spray can be used for up to 4 weeks. Fluocinonide's higher strength (0.1%) should only be used for 2 weeks, while the lower strength (0.05%) can be used for longer but not chronically. Betamethasone is generally stronger than fluocinonide, and its augmented formulations absorb faster and are more potent. Both medications should not be used on sensitive areas like the face, groin, or armpits, but fluocinonide's lower strength might be used on the face for short periods under a doctor's guidance. Both medications can cause hormone changes and skin reactions if used improperly or for too long.

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.