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Compare Vanos vs. Cloderm

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fluocinonide (Vanos) and clocortolone (Cloderm) are both topical corticosteroids used to treat skin inflammation and irritation, but they have some key differences. Fluocinonide is available in two strengths (0.05% and 0.1%) and comes in various forms like cream, ointment, gel, and topical solution, while clocortolone is only available as a cream. Fluocinonide is a stronger steroid compared to clocortolone, which is a medium-strength steroid. This means fluocinonide might be more effective for severe symptoms, but it also has more restrictions, such as not being suitable for use on the face, underarms, or groin, especially in its higher strength. Clocortolone, on the other hand, is easier to apply but needs to be used more frequently (three times a day) and might not be strong enough for severe conditions. Both medications should be used for the shortest time possible to avoid side effects like skin thinning and hormonal changes.

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