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Clocortolone Pivalate Coupon - Clocortolone Pivalate 45g of 0.1% tube of cream

clocortolone pivalate

Generic Cloderm
Used for Eczema, Psoriasis, Itching, Seborrheic Dermatitis, Skin Allergy
Used for Eczema, Psoriasis, Itching, Seborrheic Dermatitis, Skin Allergy

Clocortolone (Cloderm) is a topical corticosteroid (or steroid) that's used to treat many types of skin problems that cause itchiness and inflammation (swelling and redness). This medication comes as a cream that's applied to the skin three times per day. Side effects aren't common but can include a burning sensation, dry skin, and skin irritation where the cream is applied.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on August 7, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesImagesReferencesPricesMedicare
basics-icon

What is Clocortolone (Cloderm)?

What is Clocortolone (Cloderm) used for?

  • Inflammatory skin conditions

How Clocortolone (Cloderm) works

Clocortolone (Cloderm) is a topical corticosteroid, or a topical steroid. It lowers the amount of certain chemicals in the body that cause inflammation in your skin. This helps relieve symptoms like redness and swelling on the skin and itchy skin.

Are you looking for information on clobetasol (Clobex) instead?

Drug Facts

Common BrandsCloderm
Drug ClassCorticosteroid
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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$314.45(save 71.15%)
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$90.73
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What are the side effects of Clocortolone (Cloderm)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Side effects aren't common. See Other Side Effects.

Other Side Effects

  • Burning sensation
  • Dry skin
  • Itchy skin
  • Skin irritation

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Burning, itching, crusting, or peeling of treated skin
  • Fragile or thinning skin that bruises easily
  • Skin infection—skin redness, swelling, warmth, or pain
  • Small, red, pus-filled bumps on skin around hair follicles

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Mild skin irritation, redness, or dryness
  • Unexpected hair growth at application site
pros-and-cons

Pros and cons of Clocortolone (Cloderm)

thumbs-up

Pros

A cream that's easy to apply

Treats many different skin conditions

Safe to use short term for children

Few side effects

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Cons

Need to apply three times daily, which is more often than similar steroid medications

Risk of skin thinning with long-term use

Might not work well for severe skin conditions

pharmacist-tips

Pharmacist tips for Clocortolone (Cloderm)

pharmacist

  • Wash your hands well before and after you apply clocortolone (Cloderm) to your skin. This helps prevent the medication from accidentally getting in your eyes. Rinse your eye well with water for at least 15 minutes if you get the cream in your eye.

    • Apply clocortolone (Cloderm) as a thin layer to the affected area(s) of skin and rub it in gently. Avoid applying the cream near your eyes. Also avoid putting the cream on cuts or scrapes to lower the risk of the medication getting into your body and causing serious side effects.

      • Use the least amount of clocortolone (Cloderm) possible for the shortest amount of time to treat your skin condition. This helps avoid side effects, such as skin thinning and skin irritation. Only use clocortolone (Cloderm) as prescribed.

        • Don't place bandages or dressings over the areas where you applied clocortolone (Cloderm) unless your prescriber says it's okay. Covering the treated area with tight bandages or dressings can cause more medication to get absorbed into your body than intended; this can raise your risk of side effects like skin irritation.

          • For babies and small children who need clocortolone (Cloderm) to treat the skin in the diaper area, parents should avoid having them wear diapers or plastic pants that are too tight. This can cover the medicated area too tightly, which can cause more medication to get absorbed through the skin and lead to more side effects.

            • Don't use other topical steroids while you're using clocortolone (Cloderm) unless your prescriber said it's safe for you. Applying more than one topical steroid can raise your risk for side effects like skin redness and skin irritation.

              • If you have a skin infection that's causing inflammation, you might be prescribed an additional medication alongside clocortolone (Cloderm) to help treat the skin infection. Let your HCP know if you notice worsening redness, pain, or swelling or any pus where you're applying clocortolone (Cloderm). You might have to stop using clocortolone (Cloderm) until your skin infection gets treated.

                • Tell your healthcare professional if you're pregnant or breastfeeding. Discuss the risks and benefits of using clocortolone (Cloderm) with your healthcare professional.

                  faqs

                  Frequently asked questions about Clocortolone (Cloderm)

                  Is clocortolone (Cloderm) a steroid?
                  Yes, clocortolone (Cloderm) is a topical steroid that's used to lessen symptoms of skin inflammation, such as redness, itching, and swelling. Clocortolone (Cloderm) is a medium-potency topical steroid; potency is another way to describe how strong clocortolone (Cloderm) is compared to other topical steroids.
                  Can you buy clocortolone (Cloderm) over the counter?
                  No, clocortolone (Cloderm) isn't available over the counter. It's only available by prescription from a healthcare professional. The only topical steroids that you can buy over the counter are hydrocortisone 0.5% and 1%, but they aren't as strong as clocortolone (Cloderm).
                  How long does it take for clocortolone (Cloderm) to work?
                  It's not exactly clear how long it takes for clocortolone (Cloderm) to work to relieve your symptoms. But it'll probably depend on what skin condition you have and how severe it is. For example, people who used clocortolone (Cloderm) to treat eczema saw an improvement in their skin symptoms within 4 days of starting treatment during clinical studies. Follow up with your prescriber about whether clocortolone (Cloderm) seems to be improving your skin condition.
                  Can clocortolone (Cloderm) be used on the face?
                  Yes, you can use clocortolone (Cloderm) on the face if your prescriber specifically instructed you to do so to treat your skin condition. Just make sure to avoid getting the medication near or in your eyes. Studies showed that clocortolone (Cloderm) is well tolerated and also works well for skin inflammation on the face.
                  Can clocortolone (Cloderm) be used for yeast infections?
                  No, clocortolone (Cloderm) doesn't treat a yeast infection. Although clocortolone (Cloderm) can help relieve inflammation from a skin yeast infection, it doesn't directly fight against the yeast. Don't apply clocortolone (Cloderm) into the vagina to treat a vaginal yeast infection.
                  Does clocortolone (Cloderm) expire?
                  Yes, clocortolone (Cloderm) can expire. Look for the expiration date that's printed on the box that the medication comes in or on the bottle or tube of cream. Don't use clocortolone (Cloderm) past the expiration date because it might not work as well to treat your skin condition.
                  Is clocortolone (Cloderm) the same as clobetasol?
                  No, clocortolone (Cloderm) and clobetasol aren't the same. They're both topical steroids, but clobetasol is more potent (or stronger) than clocortolone (Cloderm). Because of this, clobetasol is typically used for more severe skin conditions. Clobetasol is also available in many forms, such as a lotion, gel, cream, ointment, and shampoo. On the other hand, clocortolone (Cloderm) is only available as a cream. Speak with a healthcare professional to learn more about comparing the two medications.
                  What's the difference between clocortolone (Cloderm) and hydrocortisone?
                  Both clocortolone (Cloderm) and hydrocortisone are topical steroids that are used to treat inflammation and itching from many skin conditions. Clocortolone (Cloderm) just comes as a cream, but there are many forms of hydrocortisone available, such as a lotion, topical solution, cream, and ointment. Some forms of hydrocortisone are the least potent among the topical steroids, and other forms of hydrocortisone are considered to have "medium" potency. Clocortolone (Cloderm) is a topical steroid with "medium" potency. Potency is a way to describe how strong the topical steroid is compared to the others. In addition, some forms of hydrocortisone are available over the counter but clocortolone (Cloderm) is only available by prescription. Speak with a healthcare professional to help you compare between clocortolone (Cloderm) and hydrocortisone.
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                  What are the risks and warnings for Clocortolone (Cloderm)?

                  Clocortolone (Cloderm) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Altered stress hormone levels

                  • Risk factors: Applying clocortolone (Cloderm) to large areas of the body | Applying clocortolone (Cloderm) for a long time | Applying more than one topical steroid onto the skin | Covering the medicated area | Applying onto damaged skin | Young children

                    It's possible for your body to absorb too much clocortolone (Cloderm) through the skin in certain situations. This includes applying the medication to larger areas of skin over longer periods of time and covering the treated area with tight bandages.

                    Having too much clocortolone (Cloderm) in your body can causes changes in your stress hormone levels (e.g., cortisol levels), which can affect many bodily functions. This can lead to symptoms, such as tiredness, nausea, and muscle aches. These symptoms usually go away after you stop using the medication, but you might need additional treatment if it's severe. And very rarely, more serious problems related to having too much medication in the body can include having higher blood sugar levels and, in children, possibly delayed growth.

                    Apply clocortolone (Cloderm) only as directed. Don't apply too much medication and don't use it for a longer period of time than prescribed. Also don't cover the medicated area with bandages or dressings unless your prescriber tells you to. If your prescriber thinks that clocortolone (Cloderm) is affecting your body's hormone production, they might recommend that you apply it less often or switch you to a different medication.

                    dosage

                    Clocortolone (Cloderm) dosage forms

                    The average cost for 1 tube of 45g of 0.1% of Clocortolone (Cloderm) is $90.73 with a free GoodRx coupon. This is 71.15% off the average retail price of $314.45.
                    cream pump
                    Cream pump
                    DosageQuantityPrice as low asPrice per unit
                    75g of 0.1%1 pump$143.86$143.86
                    tube of cream
                    Tube of cream
                    DosageQuantityPrice as low asPrice per unit
                    45g of 0.1%1 tube$90.73$90.73
                    90g of 0.1%1 tube$170.74$170.74

                    Typical dosing for Clocortolone (Cloderm)

                    Apply a thin layer of cream to the affected area(s) of your skin three times a day. Gently rub the cream into the skin.

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                    How much does Clocortolone (Cloderm) cost?

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                    Cloderm (brand)
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                    Clocortolone (Cloderm) (generic)
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                    alternatives

                    What are alternatives to Clocortolone (Cloderm)?

                    There are a number of medications that your doctor can prescribe in place of Clocortolone (Cloderm). Compare a few possible alternatives below.
                    Clocortolone (Cloderm)
                    Used for:

                    • Inflammatory skin conditions

                    $90.73 Lowest GoodRx priceView Prices
                    Triamcinolone
                    Used for:

                    • Inflammatory skin conditions

                    $66.20 Lowest GoodRx priceView Prices
                    Mometasone furoate
                    Used for:

                    • Skin rashes and other skin irritation

                    $41.20 Lowest GoodRx priceView Prices
                    images

                    Clocortolone (Cloderm) images

                    white - Clocortolone Pivalate 0.1% Topical Cream
                    This medicine is White Tube Of Cream.white - Clocortolone Pivalate 0.1% Topical Cream

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                    References

                    Best studies we found

                    Aaron, D. M. (2023). Candidiasis (yeast infection). Merck Manual Consumer Version.

                    Alexandraki, K. I., et al. (2021). Adrenal suppression. Endotext.

                    American Optometric Association. (n.d.). Protecting your eyes at work.

                    View All References (5)

                    Del Rosso, J. Q., et al. (2012). A comprehensive review of clocortolone pivalate 0.1% cream: structural development, formulation characteristics, and studies supporting treatment of corticosteroid-responsive dermatoses. The Journal of Clinical and Aesthetic Dermatology.

                    Del Rosso, J. Q., et al. (2012). Figure 2. Clocortolone pivalate 0.1% cream in the treatment of atopic dermatitis/eczema. The Journal of Clinical and Aesthetic Dermatology.

                    National Eczema Association. (n.d.). Risks of topical corticosteriods.

                    National Psoriasis Foundation. (n.d.). Potency chart.

                    Taro Pharmaceuticals U.S.A., inc. (20221). Clocortolone pivalate cream [package insert]. DailyMed.

                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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