Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Cloderm vs. Clobetasol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Clocortolone (Cloderm)
    Clobetasol
  • Clocortolone (Cloderm)
    Clobetasol

  • Summary of Cloderm vs. Clobetasol

    Summary for Corticosteroid
    Prescription only

    Clocortolone (Cloderm) is a topical corticosteroid (or steroid) that's used to treat many types of skin problems that cause itchiness and inflammation (swelling and redness). This medication comes as a cream that's applied to the skin three times per day. Side effects aren't common but can include a burning sensation, dry skin, and skin irritation where the cream is applied.

    Summary for Corticosteroid
    Prescription only

    Clobetasol is a super potent (very strong) corticosteroid that's applied to the skin. It helps relieve skin inflammation and irritation from moderate-to-severe skin problems, like psoriasis. Clobetasol is available in many different formulations. This includes a cream, ointment, shampoo, topical solution, and foam. Most formulations are for people 12 years and older. But others, like the shampoo and lotion, are for adults only. Some side effects include burning, stinging, and irritation where it's applied. Clobetasol has both brand-name and generic options.

  • Indications of Cloderm vs. Clobetasol

    Indications for
    •Inflammatory skin conditions
    Indications for
    •Skin rashes and itchy skin - all topical forms except shampoo
    •Plaque psoriasis not on the scalp - all topical forms except shampoo
    •Moderate-to-severe scalp psoriasis - shampoo and certain foams only

  • Pros and Cons of Cloderm vs. Clobetasol

    Pros and Const for Corticosteroid
    Pros
    •A cream that's easy to apply
    •Treats many different skin conditions
    •Safe to use short term for children
    •Few side effects
    Cons
    •Need to apply three times daily, which is more often than similar steroid medications
    •Risk of skin thinning with long-term use
    •Might not work well for severe skin conditions
    Pros and Const for Corticosteroid
    Pros
    •One of the most potent (strongest) topical steroids
    •Applied directly to the affected area(s) of skin
    •Many formulations to choose from, such as ointment, cream, and spray
    •Works well for managing psoriasis symptoms
    Cons
    •For short-term use only (usually no more than 2 weeks at a time) to prevent skin thinning and other problems
    •Not safe to use on the face, armpits, or groin
    •Some formulations are only for adults (e.g., shampoo, lotion, spray)
    •Not known if safe to use while pregnant or breastfeeding

  • Common Side Effects of Cloderm vs. Clobetasol

    Common Side Effects for
    •Side effects aren't common. See Other Side Effects.
    Common Side Effects for
    •Burning
    •Stinging
    •Skin irritation
    •Itching

  • Warnings of Cloderm vs. Clobetasol

    Common Side Effects for
    •Altered stress hormone levels
    Common Side Effects for
    •More skin reactions with longer use and coverings
    •Changes in stress hormone levels
    •Topical steroid withdrawal
    •Higher risk of cataracts and glaucoma
    •Treat any skin infections appropriately
    •Flammable (clobetasol foam, solution, and spray only)

  • Prices with our coupons for Cloderm vs. Clobetasol

    Learn more about Clocortolone
    Learn more about Clobetasol

Compare other Eczema and Psoriasis drugs

Luxiq vs ClodermVanos vs ClodermCimzia vs HumiraCosentyx vs HumiraEnbrel vs HumiraEntyvio vs HumiraHalog vs DesonateHumira vs DovonexHumira vs PrednisoneHumira vs SimponiHumira vs TaclonexHumira vs TazoracHumira vs VanosLuxiq vs DesonateLuxiq vs VanosOrencia vs HumiraOtezla vs HumiraRemicade vs HumiraRinvoq vs HumiraSkyrizi vs HumiraTremfya vs HumiraVanos vs DesonateXeljanz vs Humira
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.