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Compare Cloderm vs. Hydrocortisone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Clocortolone (Cloderm)
    Topical hydrocortisone
  • Clocortolone (Cloderm)
    Topical hydrocortisone

  • Summary of Cloderm vs. Hydrocortisone

    Summary for Corticosteroid
    Prescription only

    Clocortolone (Cloderm) is a topical corticosteroid (or steroid) that's used to treat many types of skin problems that cause itchiness and inflammation (swelling and redness). This medication comes as a cream that's applied to the skin three times per day. Side effects aren't common but can include a burning sensation, dry skin, and skin irritation where the cream is applied.

    Summary for Corticosteroid

    Topical hydrocortisone is a steroid medication used to treat different skin conditions, such as eczema. It's available in many different formulations, including cream, ointment, lotion, and solution. Some strengths are found over the counter (e.g., hydrocortisone 1%), while you need a prescription for others (e.g., hydrocortisone 2.5%). In general, most people experience few to no side effects while using topical hydrocortisone as directed. Rarely, topical hydrocortisone might cause topical steroid withdrawal (TSW). Watch out for skin rashes and irritations that get worse after stopping this medication.

  • Indications of Cloderm vs. Hydrocortisone

    Indications for
    •Inflammatory skin conditions
    Indications for

    Short-term relief of skin irritations (e.g., itching) due to:

    •Skin inflammation
    •Skin rashes
    •Eczema
    •Psoriasis
    •Insect bites
    •Poison ivy or oak
    •Skin allergies
    •Dry scalp
    •Genital or rectal irritation

  • Pros and Cons of Cloderm vs. Hydrocortisone

    Pros and Const for Corticosteroid
    Pros
    •A cream that's easy to apply
    •Treats many different skin conditions
    •Safe to use short term for children
    •Few side effects
    Cons
    •Need to apply three times daily, which is more often than similar steroid medications
    •Risk of skin thinning with long-term use
    •Might not work well for severe skin conditions
    Pros and Const for Corticosteroid
    Pros
    •Available as a lower-cost, generic medication
    •Available over the counter
    •Many formulations to choose from, such as ointment, cream, and solution
    Cons
    •Short-term use only, otherwise it might cause skin thinning and high blood sugar
    •Applied multiple times a day
    •Might affect your body's ability to fight off infections

  • Common Side Effects of Cloderm vs. Hydrocortisone

    Common Side Effects for
    •Side effects aren't common. See Other Side Effects.
    Common Side Effects for
    •Burning
    •Itching
    •Skin irritation
    •Dry skin
    •Inflamed hair follicles

  • Warnings of Cloderm vs. Hydrocortisone

    Common Side Effects for
    •Altered stress hormone levels
    Common Side Effects for
    •Hormone problems and withdrawal
    •High blood sugar
    •New or worsened skin infection
    •Skin problems

  • Prices with our coupons for Cloderm vs. Hydrocortisone

    Learn more about Clocortolone
    Learn more about Topical hydrocortisone

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