Hydrocortisone (Cortef) is an inexpensive drug used to treat inflammation of the skin, joints, lungs, and other organs. It is less popular than comparable drugs. It is available in generic and brand versions. Generic hydrocortisone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Get Proctozone HC for as low as $6.86, which is 92% off the average retail price of $85.68 for the most common version, by using a GoodRx coupon.