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Remicade Coupon - Remicade 100mg vial

Remicade

infliximab
Used for Plaque Psoriasis, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Crohn's Disease, Ankylosing Spondylitis
Used for Plaque Psoriasis, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Crohn's Disease, Ankylosing Spondylitis

Remicade (infliximab) is an injectable medication used to treat many autoimmune conditions, including ulcerative colitis and Crohn's disease. It's given through an intravenous (IV) infusion by a healthcare provider.

Last reviewed on December 16, 2021
basics-icon

What is Remicade (infliximab)?

What is Remicade (infliximab) used for?

  • Moderate-to-severe Crohn's disease (CD)

  • Moderate-to-severe ulcerative colitis (UC)

  • Moderate-to-severe rheumatoid arthritis (RA)

  • Ankylosing spondylitis (AS)

  • Psoriatic arthritis (PsA)

  • Severe plaque psoriasis (PsO)

How Remicade (infliximab) works

Remicade (infliximab) is a biological disease-modifying antirheumatic drug (DMARD) that blocks a protein called tumor necrosis factor (TNF). By blocking TNF, Remicade (infliximab) lowers inflammation in your body to treat symptoms caused by many autoimmune conditions.

Drug Facts

Drug ClassBiologic DMARD
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

More on Remicade (infliximab) essentials

basics-icon

What are the side effects of Remicade (infliximab)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Infections
  • Nausea
  • Infusion-related reactions (e.g., headache, flushing, shortness of breath, rash)
  • Headache
  • Diarrhea
  • Stomach pain
  • Sore throat
  • Cough
  • Rash
  • Bronchitis
  • Indigestion
  • Tiredness
  • General pain
  • Joint pain

Other Side Effects

  • Itching
  • High or low blood pressure
  • Swelling

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe or deadly infections: fever, difficulty breathing, diarrhea, weakness, cough, stomach pain, sweating, chills, burning when you urinate, urinating more frequently
  • Cancer: loss of appetite, fatigue, lumps on skin, swollen lymph nodes in your neck, armpits, or groin, fatigue, weight loss, nosebleeds, vaginal discharge, pelvic or back pain
  • Serious allergic reactions: hives, itching, swelling of face or tongue, difficulty breathing, low blood pressure
  • Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, unable to exercise, tiredness, weakness
  • Stroke: facial drooping on one side, slurred speech, weakness, dizziness, headache, confusion, vision loss
  • Heart problems: high blood pressure, fast and irregular heart beat, chest pain, heart attacks
  • Liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion
  • Low blood cell counts: fever, pale skin, fast heart rate, lightheadedness, blood in your urine or stool
  • Drug-induced lupus: chest discomfort or pain, short of breath, joint or muscle pain, rash on cheecks or arms

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

bladder pain

bloody or cloudy urine

blurred vision

body aches or pain

chest pain

chills

cough

cough producing mucus

difficult, burning, or painful urination

difficulty breathing

dizziness

dryness or soreness of the throat

ear congestion

fever

frequent urge to urinate

headache

hoarseness

hives, itching, or rash

loss of voice

lower back or side pain

muscle pain

nervousness

pain or swelling in the arms or legs

pain or tenderness around the eyes and cheekbones

painful or difficult urination

pale skin

pounding in the ears

runny or stuffy nose

slow or fast heartbeat

sneezing

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach pain

tender, swollen glands in the neck

tightness in the chest

trouble breathing

trouble swallowing

unusual bleeding or bruising

unusual tiredness or weakness

voice changes

Rare

Bleeding gums

blood in the stool

blue lips and fingernails

changes in skin color or tenderness of the foot or leg

chest discomfort

confusion

coughing that sometimes produces a pink frothy sputum

dark urine

decreased urination

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry mouth

fast or noisy breathing

feeling of discomfort

general feeling of illness

general tiredness and weakness

high fever

hives

increased sweating

irregular or pounding heartbeat

light-colored stools

muscle aches

nausea

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid, shallow breathing

swelling of the joints

sunken eyes

thirst

upper right abdominal or stomach pain

vomiting

unusual weight loss

wrinkled skin

yellow skin and eyes

Incidence not known

Back pain, sudden and severe

blistering, peeling, loosening of the skin

bloody nose

burning, tingling, numbness or pain in the hands, arms, feet, or legs

change in mental status

clay-colored stools

dark or bloody urine

diarrhea

difficulty with speaking

dilated neck veins

double vision

heavier menstrual periods

inability to move the arms, legs, or facial muscles

inability to speak

loss of appetite

muscle weakness, sudden and progressing

red, irritated eyes

red skin lesions, often with a purple center

seizures

sensation of pins and needles

slow or irregular breathing

slow speech

stabbing pain

temporary vision loss

vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Belching

difficulty in moving

feeling of warmth

heartburn

indigestion

muscle stiffness

redness of the face, neck, arms, and occasionally, upper chest

Less common

Constipation, severe

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Remicade (infliximab)

thumbs-up

Pros

Can be used for many autoimmune conditions

Typically only needs to be given every 6 to 8 weeks

Can be used in children 6 years of age and older for UC and CD

thumbs-down

Cons

Can only be given as an IV infusion by a healthcare professional

Can cause a lot of side effects

Brand name only, which can be expensive

pharmacist-tips

Pharmacist tips for Remicade (infliximab)

pharmacist
  • Remicade (infliximab) can raise your risk of getting a severe or life-threatening infection. If you develop symptoms of an infection (e.g., fever, cough, difficulty breathing, diarrhea, weakness, sweating, chills) after starting Remicade (infliximab), go to the hospital right away so you can be tested for an infection. You might have to stop taking Remicade (infliximab) so your body can fight the infection.

    • Remicade (infliximab) is given only as an IV infusion by trained healthcare professionals in a clinic or infusion center. The infusion will take about 2 hours. Make sure you know when your infusions are scheduled so you don't miss a dose.

      • Your provider might give you medications, such as acetaminophen (Tylenol) or diphenhydramine (Benadryl), right before the Remicade (infliximab) infusion to prevent reactions that can happen during the infusion, such as flushing, headache, and rash.

        • Your provider will monitor you during and after your Remicade (infliximab) infusion for side effects and to see how well the treatment is working.

          faqs

          Frequently asked questions about Remicade (infliximab)

          How often do I need to get Remicade (infliximab)?
          This will depend on what condition you're being treated for. In general, when first starting Remicade (infliximab), it's typically given every 2 to 4 weeks for 3 doses. Then, the maintenance dose is typically given every 2 months, but for AS, it's given every 6 weeks.
          How long do I have to take Remicade (infliximab)?
          There isn't a specific amount of time that you'll need to take Remicade (infliximab). Your provider will likely have you continue taking the medication as long as it's helping your condition and you're not having side effects.
          What is the difference between Remicade (infliximab) and Avsola, Inflectra, or Renflexis?
          Avsola, Inflectra, and Renflexis are known as biosimilars to Remicade (infliximab). A biosimilar is a biologic medication with similar function, structure, and effectiveness as the original biologic that was first approved by the FDA. Avsola, Inflectra, Renflexis, and Remicade (infliximab) all treat the same autoimmune conditions as Remicade. Read on for more information about the specific differences between Remicade and Inflectra.
          Can I receive vaccines if I'm taking Remicade (infliximab)?
          You can still receive certain vaccines, including the flu shot, while taking Remicade (infliximab). However, you shouldn't receive live vaccines because it's not known if they are safe while you're taking Remicade (infliximab). Examples of live vaccines include the FluMist Quadrivalent (live attenuated influenza vaccine), which is given through a nasal spray, the measles, mumps, rubella (MMR) vaccine, and the Bacille Calmette-Guerin (BCG) vaccine. You should be brought up to date with all vaccines before starting Remicade (infliximab). Be sure to let your provider know you're taking Remicade (infliximab) before you receive any vaccines. Also, make sure your providers know if you received this medication while you were pregnant because your baby might have a higher risk of infections. Your provider will decide when your baby can receive vaccines safely after birth.
          Can I use Remicade (infliximab) if I'm pregnant?
          The effects of Remicade (infliximab) on pregnant women and their unborn babies aren't clear, so it's not known if this medication is safe to use during pregnancy. If you're pregnant or thinking of getting pregnant, talk to your provider to see if Remicade (infliximab) is right for you.
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          warings-icon

          What are the risks and warnings for Remicade (infliximab)?

          Remicade (infliximab) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

          risk-warning

          Serious or deadly infections

          • Risk factors: Active, chronic, or recurrent infection | Age 65 years and older | Having other conditions that raise your risk of infection | Living in or traveling to places with high rates of TB or fungal infections | Taking medications that weaken your immune system (e.g., steroids or methotrexate)

            Remicade (infliximab) can affect your body's ability to fight off infections, which can raise your risk of serious or life-threatening bacterial, viral, or fungal infections. The risk is higher for people who have an active infection, people who have infections that keep coming back, adults aged 65 years and older, people with certain chronic conditions that make it easier to develop infections, and people taking medications that weaken your immune system (e.g., steroids or methotrexate).

            Remicade (infliximab) can also cause new or old tuberculosis (TB) infections to come back. Similarly, the medication can reactivate the hepatitis B virus (HBV) if you're a carrier of the virus.
            For these reasons, you'll need to get tested for both TB and HBV before starting Remicade (infliximab) and get treatment if you test positive.

            If you develop symptoms of an infection (e.g., fever, cough, difficulty breathing, diarrhea, weakness, sweating, chills) while taking Remicade (infliximab), go to the hospital right away so you can be tested for an infection. You might have to stop taking Remicade (infliximab) so your body can fight the infection. Tell your provider about your medical conditions and medications so they can make sure Remicade (infliximab) is safe for you.

            risk-warning

            Cancer

            • Risk factors: Age 18 years old and younger | Taking medications that weaken your immune system (e.g., 6-mercaptopurine (Purinethol) or azathioprine (Imuran)) | History of cancer | Severe rheumatoid arthritis

              Remicade (infliximab) might raise your risk of getting certain types of cancers, including leukemia, lymphoma, skin, or cervical cancer. The risk is higher in people 18 years old and younger, if you take other medications that weaken your immune system (e.g, 6-mercaptopurine (Purinethol) or azathioprine (Imuran)), if you have a history of cancer, or if you have severe rheumatoid arthritis. You'll likely need certain labs and occasional physical exams while you take Remicade (infliximab) to monitor your risk of cancer. If you experience symptoms such as swollen lymph nodes in your neck, armpits, or groin, fatigue, weight loss, loss of appetite, recurrent nosebleeds, lumps on your skin, vaginal discharge, pelvic or back pain, or bleeding that is heavier or longer than usual, contact your provider.

              risk-warning

              Liver problems and liver failure

              • Risk factors: History of liver problems

                Remicade (infliximab) can cause serious liver problems that can lead to liver failure or death. You might need to get regular blood tests done to make sure your liver is working properly. Seek medical attention right away if you notice swelling of your stomach, yellowing of your skin or the whites of your eyes, stool changes (black, tarry, or bloody stools), coughing or vomiting up blood, confusion, slurred speech, mood swings, or changes in personality. You might need to stop using the medication to prevent further liver damage.

                risk-warning

                Heart problems

                • Risk factors: History of heart problems

                  Remicade (infliximab) can cause new or worsening heart failure, heart attacks, fast and irregular heartbeat, and high or low blood pressure. Let your provider know if you experience any signs of heart problems (e.g., shortness of breath, swelling in the legs, ankles, or feet, fast and irregular heartbeat, difficulty exercising, tiredness or weakness, chest pain) Remicade (infliximab).

                  risk-warning

                  Low blood cell counts

                  Although rare, Remicade (infliximab) can lead to low blood cell counts. This can raise your risk of serious infections, bleeding, and anemia. If your blood counts drop too low, you'll likely need to stop taking Remicade (infliximab). If you develop any signs of infection (e.g., fever, tiredness, chills, cough, trouble breathing) or signs of bleeding (pale skin, fast heart rate, lightheadedness, blood in your urine or stool), contact your provider right away.

                  risk-warning

                  Nervous system problems

                  • Risk factors: History of a neurologic problem

                    Although rare, Remicade (infliximab) can cause new or worsening nervous system problems, including damage to the nerves and seizures. Tell your provider if you have any neurological problems before starting Remicade (infliximab) or if you get dizziness, muscle weakness or spasms, changes in vision, or loss of balance while taking Remicade (infliximab).

                    risk-warning

                    Medications to avoid

                    Don't take Remicade (infliximab) together with other biological medications, including Kineret (anakinra), Orencia (abatacept), Enbrel (etanercept) or Actemra (tocilizumab), because doing so can raise your risk of serious infections. Talk to your provider before starting any medications for your autoimmune condition.

                    dosage

                    Remicade (infliximab) dosage forms

                    Typical dosing for Remicade (infliximab)

                    Remicade (infliximab) is only given through an IV infusion by a healthcare provider. The typical dose is 300 mg IV infused over 1 hour every month.

                    interactions

                    Interactions between Remicade (infliximab) and other drugs

                    Remicade (infliximab) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Remicade (infliximab). Please note that only the generic name of each medication is listed below.

                    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

                    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    contraindications-icon

                    Remicade (infliximab) contraindications

                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Remicade (infliximab) will not be safe for you to take.
                    • Moderate or severe heart failure (for doses higher than 5 mg/kg of body weight)

                    alternatives

                    What are alternatives to Remicade (infliximab)?

                    There are a number of medications that your doctor can prescribe in place of Remicade (infliximab). Compare a few possible alternatives below.
                    Remicade (infliximab)
                    Used for:
                    • Moderate-to-severe Crohn's disease (CD)

                    • Moderate-to-severe ulcerative colitis (UC)

                    • Moderate-to-severe rheumatoid arthritis (RA)

                    • Ankylosing spondylitis (AS)

                    • Psoriatic arthritis (PsA)

                    • Severe plaque psoriasis (PsO)

                    Used for:
                    latest news

                    What is the latest news about Remicade (infliximab)?

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                    Remicade (infliximab) images

                    white - Remicade 100mg Powder for Injection
                    This medicine is White Vial.white - Remicade 100mg Powder for Injection

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