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Compare Rinvoq vs. Cimzia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Rinvoq (upadacitinib)
    Cimzia (certolizumab)
  • Rinvoq (upadacitinib)
    Cimzia (certolizumab)

  • Summary of Rinvoq vs. Cimzia

    Summary for JAK inhibitor
    Prescription only

    Rinvoq (upadacitinib) is a Janus kinase (JAK) inhibitor. It's used to treat certain inflammatory conditions, such as rheumatoid arthritis (RA), ulcerative colitis (UC), and eczema (atopic dermatitis). But it's not a first-choice option and typically only prescribed when other treatments haven't worked well. Rinvoq (upadacitinib) is taken by mouth, usually once daily. It's available as an extended-release tablet (Rinvoq) and an oral solution (Rinvoq LQ), but the two formulations aren't interchangeable. Side effects include a higher risk of infections, acne, and nausea.

    Summary for TNF blocker
    Prescription only

    Cimzia (certolizumab) is an injection that's used to treat many autoimmune conditions, such as rheumatoid arthritis, psoriasis, and Crohn's disease. This medication is given every 2 to 4 weeks. It can be used by itself or together with other medications, such as methotrexate. Side effects of Cimzia (certolizumab) include upper respiratory infections, urinary tract infections, and skin rash.

  • Indications of Rinvoq vs. Cimzia

    Indications for

    Moderate-to-severe inflammatory conditions in which other treatments haven't worked:

    •Rheumatoid arthritis (RA) in adults
    •Psoriatic arthritis (PsA) in adults and children ages 2 years and older
    •Eczema (atopic dermatitis) in adults and children ages 12 years and older
    •Ulcerative colitis (UC) in adults
    •Crohn's disease (CD) in adults
    •Ankylosing spondylitis (AS) in adults
    •Non-radiographic axial spondyloarthritis (nr-axSpA) in adults
    •Polyarticular juvenile idiopathic arthritis (pJIA) in adults and children ages 2 years and older
    Indications for
    •Moderate-to-severe Crohn's disease
    •Moderate-to-severe rheumatoid arthritis (RA)
    •Psoriatic arthritis (PsA)
    •Ankylosing spondylitis (AS)
    •Non-radiographic axial spondyloarthritis (nr-axSpA)
    •Moderate-to-severe plaque psoriasis (PsO)

  • Pros and Cons of Rinvoq vs. Cimzia

    Pros and Const for JAK inhibitor
    Pros
    •Can treat many different inflammatory conditions
    •Available as a tablet and a liquid
    •The tablet only needs to be taken once a day
    Cons
    •Can raise risk for infections
    •Not the best option for people with severe liver or kidney problems
    •Not safe for use during pregnancy
    Pros and Const for TNF blocker
    Pros
    •Can use for many autoimmune conditions
    •Only need to inject every 2 to 4 weeks
    •Available as a prefilled syringe for easier use
    •Can store prefilled syringe at room temperature for up to 7 days, if needed
    Cons
    •Can raise your risk of infection
    •Might be difficult for some people to administer properly
    •Hasn't been studied in children younger than 18 years old

  • Common Side Effects of Rinvoq vs. Cimzia

    Common Side Effects for
    •Upper respiratory tract infection (25%)
    •Acne (16%)
    •Herpes simplex virus (HSV) infection (8%)
    •Headache (6%)

    Note: Side effects listed were reported by people who took Rinvoq for eczema.

    Common Side Effects for
    •Upper respiratory infections (common cold, throat infection; 18%)
    •Rash (9%)
    •Urinary tract infections (8%)

  • Warnings of Rinvoq vs. Cimzia

    Common Side Effects for
    •Serious infections
    •Possible higher risk of death for people with rheumatoid arthritis
    •Risk of cancer
    •Possible risk of heart attack, stroke, and other blood clots
    •Severe allergic reaction
    •Stomach and gut tears
    •Abnormal lab results (e.g., blood cell counts, cholesterol levels)
    •Possible harm to unborn babies
    •Medication in stool
    Common Side Effects for
    •Serious infections
    •Cancer
    •Heart failure
    •Nervous system problems
    •Low blood cell counts
    •Allergic reactions

  • Prices with our coupons for Rinvoq vs. Cimzia

    Learn more about Rinvoq
    Learn more about Cimzia

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