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Velsipity vs. Rinvoq

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Velsipity

(etrasimod)

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Rinvoq

(upadacitinib)

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Summary for Velsipity

Prescription only

Velsipity (etrasimod) is a medication that treats ulcerative colitis (UC) in adults. It works as a sphingosine 1-phosphate (S1P) receptor modulator to help relieve gut inflammation and symptoms of UC. The usual dose is 1 tablet by mouth once a day. Velsipity (etrasimod) can cause side effects like headache and dizziness. It also has a few serious risks, including infection, heart problems, and liver damage. Velsipity (etrasimod) is available as a brand-name medication.

Indications for Velsipity

Pros and Cons for Velsipity

Pros

  • Taken by mouth, with or without food
  • Only taken once a day
  • Can be an option when other medications for UC haven't worked well enough

Cons

  • Risk of serious infections
  • Might interact with vaccines or immunosuppressants
  • Might not be safe if you have heart problems or severe liver problems

Common Side Effects for Velsipity

Warnings for Velsipity

  • Risk of infections
  • Slow heart rhythm and heart rate
  • High blood pressure
  • Liver problems
  • Eye problem (macular edema)
  • Harm to an unborn baby
  • Possible risk of skin cancer
  • Brain problems
  • Breathing problems

Summary for Rinvoq

Prescription only

Rinvoq (upadacitinib) is a Janus kinase (JAK) inhibitor. It treats many inflammatory conditions. This includes rheumatoid arthritis (RA), ulcerative colitis (UC), Crohn's disease (CD), and eczema (atopic dermatitis). It's often used when other treatments haven't worked well. Rinvoq (upadacitinib) is taken by mouth, usually once a day. It comes as an extended-release pill (Rinvoq) and an oral solution (Rinvoq LQ). These formulations aren't the same and can't be swapped easily. Side effects include nausea and a higher risk of infection.

Indications for Rinvoq

Pros and Cons for Rinvoq

Pros

  • Can treat many different inflammatory conditions
  • Available as a tablet and a liquid
  • Tablets are taken once a day

Cons

  • Can raise your risk of infections
  • Can interact with grapefruit
  • Not the best option for people with severe liver or kidney problems

Common Side Effects for Rinvoq

Warnings for Rinvoq

  • Serious infections
  • Possible higher risk of heart attack, stroke, or heart-related death in certain older adults with RA
  • Risk of cancer
  • Risk of blood clots
  • Allergic reactions
  • Stomach damage
  • Abnormal lab results (e.g., blood counts, cholesterol)
  • Harm to an unborn baby
  • Medication in stool

Prices with our coupons for Velsipity vs. Rinvoq

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Velsipity30 tablets / 2mg
$6,436.83$8,719.33
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Price Card Drug Icon
Rinvoq30 tablets / 15mg
$6,244.67$8,836.29
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