Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Velsipity vs. Zeposia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Velsipity (etrasimod)
    Zeposia (ozanimod)
  • Velsipity (etrasimod)
    Zeposia (ozanimod)

  • Summary of Velsipity vs. Zeposia

    Summary for S1P receptor modulator
    Prescription only

    Velsipity (etrasimod) is a medication that treats ulcerative colitis (UC) in adults. It works as a sphingosine 1-phosphate (S1P) receptor modulator to help relieve gut inflammation and symptoms of UC. The usual dose is 1 tablet by mouth once a day. Velsipity (etrasimod) can cause side effects like headache and dizziness. It also has a few serious risks, including infection, heart problems, and liver damage. Velsipity (etrasimod) is available as a brand-name medication.

    Summary for S1P receptor modulator
    Prescription only

    Zeposia (ozanimod) treats adults with relapsing forms of multiple sclerosis (MS). This medication can also treat adults with ulcerative colitis (UC). It works as a sphingosine 1-phosphate (S1P) receptor modulator to relieve inflammation in the body. It's a capsule you take by mouth, usually once per day (or as directed by your prescriber if you have liver problems). You use a starter pack for the first week. It helps you slowly raise your dosage to a maintenance level. Side effects include upper respiratory infections and higher liver enzymes. Zeposia (ozanimod) is only available as a brand-name medication.

  • Indications of Velsipity vs. Zeposia

    Indications for
    •Moderate-to-severe ulcerative colitis (UC) in adults
    Indications for
    •Relapsing forms of multiple sclerosis (MS) in adults
    •Moderate-to-severe ulcerative colitis (UC) in adults

  • Pros and Cons of Velsipity vs. Zeposia

    Pros and Const for S1P receptor modulator
    Pros
    •Taken by mouth, with or without food
    •Only taken once a day
    •Can be an option when other medications for UC haven't worked well enough
    Cons
    •Risk of serious infections
    •Might interact with vaccines or immunosuppressants
    •Might not be safe if you have heart problems or severe liver problems
    Pros and Const for S1P receptor modulator
    Pros
    •Taken by mouth, with or without food
    •Taken once a day
    •Starter pack available to help guide dosing at the beginning of treatment
    Cons
    •Might raise your risk of infections
    •Not safe for people with certain heart problems or severe liver problems
    •Not approved for children

  • Common Side Effects of Velsipity vs. Zeposia

    Common Side Effects for
    •Headache (9%)
    •Higher liver enzyme levels (6%)
    •Dizziness (5%)
    Common Side Effects for
    •Upper respiratory infection (26%)
    •High liver enzyme levels (10%)

  • Warnings of Velsipity vs. Zeposia

    Common Side Effects for
    •Risk of infections
    •Slow heart rhythm and heart rate
    •High blood pressure
    •Liver problems
    •Eye problem (macular edema)
    •Harm to an unborn baby
    •Possible risk of skin cancer
    •Brain problems
    •Breathing problems
    Common Side Effects for
    •Risk of infections
    •Risk of brain infection (progressive multifocal leukoencephalopathy)
    •Slow heart rate and heart rhythm
    •Higher blood pressure
    •Liver damage
    •Breathing problems
    •Eye problem called macular edema
    •Brain problem called posterior reversible encephalopathy syndrome (PRES)
    •Possible risk of skin cancer
    •Harm to an unborn baby

  • Prices with our coupons for Velsipity vs. Zeposia

    Learn more about Velsipity
    Learn more about Zeposia

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.