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Compare Rinvoq vs. Cibinqo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Rinvoq (upadacitinib)
    Cibinqo (abrocitinib)
  • Rinvoq (upadacitinib)
    Cibinqo (abrocitinib)

  • Summary of Rinvoq vs. Cibinqo

    Summary for JAK inhibitor
    Prescription only

    Rinvoq (upadacitinib) is a Janus kinase (JAK) inhibitor. It's used to treat certain inflammatory conditions, such as rheumatoid arthritis (RA), ulcerative colitis (UC), and eczema (atopic dermatitis). But it's not a first-choice option and typically only prescribed when other treatments haven't worked well. Rinvoq (upadacitinib) is taken by mouth, usually once daily. It's available as an extended-release tablet (Rinvoq) and an oral solution (Rinvoq LQ), but the two formulations aren't interchangeable. Side effects include a higher risk of infections, acne, and nausea.

    Summary for JAK inhibitor
    Prescription only

    Cibinqo (abrocitinib) is used to treat moderate-to-severe atopic dermatitis (also known as eczema) in adults and children ages 12 years and older. It's taken by mouth, typically once daily. Cibinqo (abrocitinib) isn't a first-choice option for this condition because it has a FDA black box warning for the potential to cause serious side effects, such as cancer and infections. Some of the more common side effects of this medication include nausea, cold symptoms, and headaches.

  • Indications of Rinvoq vs. Cibinqo

    Indications for

    Moderate-to-severe inflammatory conditions in which other treatments haven't worked:

    •Rheumatoid arthritis (RA) in adults
    •Psoriatic arthritis (PsA) in adults and children ages 2 years and older
    •Eczema (atopic dermatitis) in adults and children ages 12 years and older
    •Ulcerative colitis (UC) in adults
    •Crohn's disease (CD) in adults
    •Ankylosing spondylitis (AS) in adults
    •Non-radiographic axial spondyloarthritis (nr-axSpA) in adults
    •Polyarticular juvenile idiopathic arthritis (pJIA) in adults and children ages 2 years and older
    Indications for
    •Moderate-to-severe atopic dermatitis (eczema) in people age 12 years and older who didn't respond to other treatments

  • Pros and Cons of Rinvoq vs. Cibinqo

    Pros and Const for JAK inhibitor
    Pros
    •Can treat many different inflammatory conditions
    •Available as a tablet and a liquid
    •The tablet only needs to be taken once a day
    Cons
    •Can raise risk for infections
    •Not the best option for people with severe liver or kidney problems
    •Not safe for use during pregnancy
    Pros and Const for JAK inhibitor
    Pros
    •Works well at treating eczema for both adults and children age 12 years and older
    •Taken once per day by mouth
    •Can be used along with topical treatments for eczema
    •Can be taken with or without food
    Cons
    •Raises your risk for serious side effects, such as blood clots and infections
    •Not a good choice for people who have trouble swallowing because the tablets can't crushed and there isn't a liquid version available
    •Not safe for people with serious liver or kidney problems
    •Safety in pregnancy or breastfeeding isn't clear

  • Common Side Effects of Rinvoq vs. Cibinqo

    Common Side Effects for
    •Upper respiratory tract infection (25%)
    •Acne (16%)
    •Herpes simplex virus (HSV) infection (8%)
    •Headache (6%)

    Note: Side effects listed were reported by people who took Rinvoq for eczema.

    Common Side Effects for
    •Nausea (6-15%)
    •Common cold (9-12%)
    •Headache (6-8%)
    •Acne (2-5%)

  • Warnings of Rinvoq vs. Cibinqo

    Common Side Effects for
    •Serious infections
    •Possible higher risk of death for people with rheumatoid arthritis
    •Risk of cancer
    •Possible risk of heart attack, stroke, and other blood clots
    •Severe allergic reaction
    •Stomach and gut tears
    •Abnormal lab results (e.g., blood cell counts, cholesterol levels)
    •Possible harm to unborn babies
    •Medication in stool
    Common Side Effects for
    •Serious infections
    •Possible higher risk of death
    •Possible risk of cancer
    •Risk of heart attack, stroke, and other blood clots
    •Low blood cell counts
    •High cholesterol

  • Prices with our coupons for Rinvoq vs. Cibinqo

    Learn more about Rinvoq
    Learn more about Cibinqo

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