Sphingosine receptor modulators are used to treat multiple sclerosis and ulcerative colitis. These medications work by targeting the sphingosine-1-phosphate receptor, which helps to reduce inflammation and prevent immune cells from attacking healthy tissues. Most of these medications are available in oral form, making them easy to take. Examples include fingolimod (Gilenya), siponimod (Mayzent), ponesimod (Ponvory), and ozanimod (Zeposia). You can choose the form that best fits your needs.