Kesimpta vs. Briumvi for Multiple Sclerosis: Important Differences and Potential Risks.

Kesimpta

(ofatumumab)

Briumvi

(ublituximab)

Summary for Kesimpta

Prescription only

Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

Indications for Kesimpta

Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS

Pros and Cons for Kesimpta

Pros

Injections are once a month (after the first 3 injections)
Can inject at home after you're trained
Comes as prefilled syringes and Sensoready Pens
Can be kept at room temperature for up to 7 days

Cons

Doesn't cure MS
Must give as an injection under the skin
Raises your risk of infections
Not recommended for people who are pregnant

Common Side Effects for Kesimpta

Upper respiratory tract infections (39%)
Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
Headache (13%)
Reaction at the injection site (e.g., pain, redness, swelling; 11%)
Urinary tract infection (10%)

Warnings for Kesimpta

Risk of infections
Injection reactions
Lower antibody levels
Harm to an unborn baby

Summary for Briumvi

Prescription only

Briumvi (ublituximab or ublituximab-xiiy) is a medication used to treat relapsing forms of multiple sclerosis (MS). This medication is given as an infusion into your veins by a healthcare provider. After you finish the starting doses, you'll receive Briumvi (ublituximab) once every 6 months. Briumvi (ublituximab) can raise your risk for infusion-related reactions so your provider might give you pre-medications, such as a corticosteroid, before your infusion to lower the risk of these reactions.

Indications for Briumvi

Relapsing forms of multiple sclerosis (MS)

Pros and Cons for Briumvi

Pros

Works well for treating relapsing forms of MS
Given once every 6 months after the first 2 doses
Can be used in people with liver or kidney problems
Copay savings program available for people who are eligible

Cons

Needs to be given as an IV infusion by a healthcare provider
Should be avoided in pregnant females
Hasn't been studied in children
Commonly causes infusion reactions

Common Side Effects for Briumvi

Fever, chills, headaches, and other infusion-related reactions (48%)
Runny nose, sore throat, and other symptoms of upper respiratory tract infections (45%)
Cough, chest pain, and other symptoms of lower respiratory tract infections (9%)

Warnings for Briumvi

Infusion reactions
Risk of infections
Low antibodies
Potential harm to unborn babies

Prices with our coupons for Kesimpta vs. Briumvi

Kesimpta1 pen / 20mg/0.4ml

$10,789.78-

Get free coupons

More Information

Briumvi3 vials / 6ml of 150mg/6ml

$34,082.84$39,996.09

Get free coupons

More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.

Compare
Kesimpta vs. Briumvi

Kesimpta

Briumvi

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Briumvi

Indications for Briumvi

Pros and Cons for Briumvi

Pros

Cons

Common Side Effects for Briumvi

Warnings for Briumvi

Prices with our coupons for Kesimpta vs. Briumvi

Compare other Multiple Sclerosis drugs

Browse medications by letter

Good news for your inbox

Kesimpta

Briumvi

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Briumvi

Indications for Briumvi

Pros and Cons for Briumvi

Pros

Cons

Common Side Effects for Briumvi

Warnings for Briumvi