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Compare Kesimpta vs. Tecfidera

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Kesimpta (ofatumumab)
    Dimethyl fumarate (Tecfidera)
  • Kesimpta (ofatumumab)
    Dimethyl fumarate (Tecfidera)

  • Summary of Kesimpta vs. Tecfidera

    Summary for Monoclonal antibody
    Prescription only

    Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

    Summary for Fumaric acid derivative
    Prescription only

    Dimethyl fumarate (Tecfidera) is used to treat adults with certain types of multiple sclerosis (MS), a condition that affects your nervous system. This medication is a disease-modifying therapy (DMT) that belongs to the drug class called fumaric acid derivatives. Dimethyl fumarate (Tecfidera) is available as a brand-name medication and a lower-cost generic. The capsules are taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

  • Indications of Kesimpta vs. Tecfidera

    Indications for
    •Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS
    Indications for
    •Relapsing forms of multiple sclerosis (MS)

  • Pros and Cons of Kesimpta vs. Tecfidera

    Pros and Const for Monoclonal antibody
    Pros
    •Injections are once a month (after the first 3 injections)
    •Can inject at home after you're trained
    •Comes as prefilled syringes and Sensoready Pens
    •Can be kept at room temperature for up to 7 days
    Cons
    •Doesn't cure MS
    •Must give as an injection under the skin
    •Raises your risk of infections
    •Not recommended for people who are pregnant
    Pros and Const for Fumaric acid derivative
    Pros
    •Works well to lessen MS relapses
    •Can take with or without food
    •Available as a lower-cost generic medication
    •No known interactions with other medications or supplements
    Cons
    •Need to take twice a day
    •Might need MRI scans to see whether the medication is working for you
    •Might need to have regular blood work done to make sure the medication isn't causing any liver problems
    •Can cause more bothersome stomach-related side effects than Vumerity (diroximel fumarate)

  • Common Side Effects of Kesimpta vs. Tecfidera

    Common Side Effects for
    •Upper respiratory tract infections (39%)
    •Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
    •Headache (13%)
    •Reaction at the injection site (e.g., pain, redness, swelling; 11%)
    •Urinary tract infection (10%)
    Common Side Effects for
    •Flushing (40%)
    •Stomach pain (18%)
    •Diarrhea (14%)
    •Nausea (12%)
    •Vomiting (9%)
    •Itchiness (8%)
    •Rash (8%)

  • Warnings of Kesimpta vs. Tecfidera

    Common Side Effects for
    •Risk of infections
    •Injection reactions
    •Lower antibody levels
    •Harm to an unborn baby
    Common Side Effects for
    •Severe allergic reactions
    •Serious infections
    •Low white blood cell counts (lymphopenia)
    •Liver damage
    •Flushing
    •Serious stomach and intestine problems

  • Prices with our coupons for Kesimpta vs. Tecfidera

    Learn more about Kesimpta
    Learn more about Dimethyl fumarate

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