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Compare Mayzent vs. Betaseron

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Mayzent (siponimod) and Betaseron (interferon beta-1b) are both treatments for relapsing forms of multiple sclerosis (MS), but they differ in several ways. Mayzent is an oral medication taken once daily, while Betaseron is an injectable medication administered every other day. Mayzent works by modulating the sphingosine 1-phosphate receptor to prevent white blood cells from causing nerve damage, whereas Betaseron is a biologic that affects the immune system, though its exact mechanism is unknown. Mayzent requires genetic testing before starting treatment to determine the appropriate dose, while Betaseron does not. Common side effects of Mayzent include headache and high blood pressure, whereas Betaseron often causes flu-like symptoms and injection site reactions. Additionally, Mayzent is only available as a brand-name medication, while Betaseron has a similar counterpart called Extavia. Both medications have serious potential side effects, but they differ in their specific risks and administration methods.

  • Mayzent (siponimod)
    Betaseron (interferon beta-1b)
  • Mayzent (siponimod)
    Betaseron (interferon beta-1b)

  • Summary of Mayzent vs. Betaseron

    Summary for Sphingosine 1-phosphate receptor modulator
    Prescription only

    Mayzent (siponimod) is a disease-modifying treatment option for relapsing multiple sclerosis (MS) in adults. It can lower the chances of worsening MS and lower the number of MS relapses. Mayzent (siponimod) is a tablet that's taken by mouth. Common side effects include headache, high blood pressure, and falls. Mayzent (siponimod) is currently available as a brand-name only.

    Summary for Biologic
    Prescription only

    Betaseron (interferon beta-1b) is an injectable biologic medication used to treat relapsing forms of multiple sclerosis (MS). It's given every other day and can cause flu-like symptoms.

  • Indications of Mayzent vs. Betaseron

    Indications for
    •Relapsing forms of multiple sclerosis (MS)
    Indications for
    •Relapsing forms of multiple sclerosis

  • Pros and Cons of Mayzent vs. Betaseron

    Pros and Const for Sphingosine 1-phosphate receptor modulator
    Pros
    •Works well to slow worsening of MS and lower the number of MS relapses
    •Taken by mouth once per day
    •Doesn't require frequent visits to the clinic or infusion center to receive your dose
    Cons
    •Requires several tests before starting (e.g., genetic testing, electrocardiogram, blood tests)
    •Might not be a good option for people with heart or serious liver problems
    •Not safe during pregnancy
    Pros and Const for Biologic
    Pros
    •Good treatment option for relapsing MS
    •Medication that's not mixed yet can be stored at room temperature, so it's convenient if you're traveling
    •An automatic injector is available for easier administration and tracking progress.
    Cons
    •Needs to be injected every 2 days
    •Can have a lot of side effects
    •Can't be used in children
    •Might be difficult for some people to prepare and administer correctly

  • Common Side Effects of Mayzent vs. Betaseron

    Common Side Effects for
    •Headache (15%)
    •High blood pressure (13%)
    •Higher liver enzyme levels in the blood (11%)
    •Falls (11%)
    •Swelling of the arms and legs (edema, 8%)
    •Nausea (7%)
    •Dizziness (7%)
    •Diarrhea (6%)
    •Low heart rate (6%)
    •Pain in arms or legs (6%)
    Common Side Effects for
    •Low blood cell counts (86%)
    •Injection site reactions: pain, swelling, bleeding (78%)
    •Flu-like symptoms: fever, chills, muscle pain, weakness, sweating (57%)
    •Muscle weakness (53%)
    •Headache (50%)
    •Pain (42%)
    •Stiff muscles (40%)
    •Fever (31%)
    •Muscle pain (23%)
    •Chills (21%)
    •Difficulty sleeping (21%)
    •Rash (21%)
    •Loss of balance/coordination (17%)
    •Stomach pain (16%)
    •Swelling in legs or hands (12%)
    •Urinating more (11%)

  • Warnings of Mayzent vs. Betaseron

    Common Side Effects for
    •Infections
    •Eye problems
    •Slow heart rate
    •Breathing problems
    •Liver damage
    •Risk of skin cancer
    •Harm to unborn babies
    •Brain problem called posterior reversible encephalopathy syndrome (PRES)
    Common Side Effects for
    •Worsening liver problems and liver failure
    •Depression and thoughts of suicide
    •Worsening heart failure
    •Injection site necrosis (ISN)
    •Low white blood cell count
    •Blood problems
    •Drug-induced lupus

  • Prices with our coupons for Mayzent vs. Betaseron

    Learn more about Mayzent
    Learn more about Betaseron

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