Kesimpta vs. Vumerity for Multiple Sclerosis: Important Differences and Potential Risks.

Kesimpta

(ofatumumab)

Vumerity

(diroximel fumarate)

Summary for Kesimpta

Prescription only

Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

Indications for Kesimpta

Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS

Pros and Cons for Kesimpta

Pros

Injections are once a month (after the first 3 injections)
Can inject at home after you're trained
Comes as prefilled syringes and Sensoready Pens
Can be kept at room temperature for up to 7 days

Cons

Doesn't cure MS
Must give as an injection under the skin
Raises your risk of infections
Not recommended for people who are pregnant

Common Side Effects for Kesimpta

Upper respiratory tract infections (39%)
Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
Headache (13%)
Reaction at the injection site (e.g., pain, redness, swelling; 11%)
Urinary tract infection (10%)

Warnings for Kesimpta

Risk of infections
Injection reactions
Lower antibody levels
Harm to an unborn baby

Summary for Vumerity

Prescription only

Vumerity (diroximel fumarate) is approved for treating relapsing forms of multiple sclerosis (MS) in adults. It's a type of disease-modifying therapy (DMT) that can help lower the number of MS relapses and slow MS from getting worse. Vumerity (diroximel fumarate) comes as a capsule that's taken by mouth twice a day. The dosage typically starts low and then is raised to the maintenance dose a week later. The most common side effects are stomach upset and flushing.

Indications for Vumerity

Relapsing forms of multiple sclerosis (MS)

Pros and Cons for Vumerity

Pros

Taken by mouth
Can help lower the number of MS relapses per year
Might cause less stomach upset than dimethyl fumarate (Tecfidera)
Few drug interactions

Cons

Must take twice a day
Often causes flushing
Should avoid taking with high-fat and high-calorie meals
Can take a few months to see the full benefit of the medication

Common Side Effects for Vumerity

Flushing (40%)
Stomach pain (18%)
Diarrhea (14%)
Nausea (12%)

Warnings for Vumerity

Severe allergic reaction
Flushing
Risk of serious infections
Low white blood cell counts
Liver damage
Serious stomach or gut problems

Prices with our coupons for Kesimpta vs. Vumerity

Kesimpta1 pen / 20mg/0.4ml of

$10,789.78-

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Vumerity1 bottle / Maintenance Dose of 231mg

$10,144.97-

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Kesimpta vs. Vumerity

Kesimpta

Vumerity

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Vumerity

Indications for Vumerity

Pros and Cons for Vumerity

Pros

Cons

Common Side Effects for Vumerity

Warnings for Vumerity

Prices with our coupons for Kesimpta vs. Vumerity

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Browse medications by letter

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Kesimpta

Vumerity

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Vumerity

Indications for Vumerity

Pros and Cons for Vumerity

Pros

Cons

Common Side Effects for Vumerity

Warnings for Vumerity