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Compare Kesimpta vs. Vumerity

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Kesimpta (ofatumumab)
    Vumerity (diroximel fumarate)
  • Kesimpta (ofatumumab)
    Vumerity (diroximel fumarate)

  • Summary of Kesimpta vs. Vumerity

    Summary for Monoclonal antibody
    Prescription only

    Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

    Summary for Fumaric acid derivative
    Prescription only

    Vumerity, also known by its generic name dimethyl fumarate, is approved in adults for treating relapsing forms of multiple sclerosis (MS). It belongs to the drug class called fumaric acid derivatives. Vumerity (diroximel fumarate) is a capsule that's taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

  • Indications of Kesimpta vs. Vumerity

    Indications for
    •Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS
    Indications for
    •Relapsing forms of multiple sclerosis (MS)

  • Pros and Cons of Kesimpta vs. Vumerity

    Pros and Const for Monoclonal antibody
    Pros
    •Injections are once a month (after the first 3 injections)
    •Can inject at home after you're trained
    •Comes as prefilled syringes and Sensoready Pens
    •Can be kept at room temperature for up to 7 days
    Cons
    •Doesn't cure MS
    •Must give as an injection under the skin
    •Raises your risk of infections
    •Not recommended for people who are pregnant
    Pros and Const for Fumaric acid derivative
    Pros
    •Lessens the number of relapses per year
    •Available in a "starter dose" bottle and "maintenance dose" bottle to help you keep track of how much medication to take
    •Few interactions with other medications
    Cons
    •Have to take twice per day
    •Flushing is a common side effect
    •Shouldn't take the medication with high-fat and high-calorie meals

  • Common Side Effects of Kesimpta vs. Vumerity

    Common Side Effects for
    •Upper respiratory tract infections (39%)
    •Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
    •Headache (13%)
    •Reaction at the injection site (e.g., pain, redness, swelling; 11%)
    •Urinary tract infection (10%)
    Common Side Effects for
    •Flushing (40%)
    •Stomach pain (18%)
    •Diarrhea (14%)
    •Nausea (12%)

  • Warnings of Kesimpta vs. Vumerity

    Common Side Effects for
    •Risk of infections
    •Injection reactions
    •Lower antibody levels
    •Harm to an unborn baby
    Common Side Effects for
    •Severe allergic reaction
    •Flushing
    •Risk for serious infections
    •Low white blood cell counts (lymphopenia)
    •Liver damage
    •Serious stomach and gut problems

  • Prices with our coupons for Kesimpta vs. Vumerity

    Learn more about Kesimpta
    Learn more about Vumerity

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