Kesimpta vs. Gilenya for Multiple Sclerosis: Important Differences and Potential Risks.

Kesimpta

(ofatumumab)

Fingolimod

(Gilenya)

Summary for Kesimpta

Prescription only

Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

Indications for Kesimpta

Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS

Pros and Cons for Kesimpta

Pros

Injections are once a month (after the first 3 injections)
Can inject at home after you're trained
Comes as prefilled syringes and Sensoready Pens
Can be kept at room temperature for up to 7 days

Cons

Doesn't cure MS
Must give as an injection under the skin
Raises your risk of infections
Not recommended for people who are pregnant

Common Side Effects for Kesimpta

Upper respiratory tract infections (39%)
Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
Headache (13%)
Reaction at the injection site (e.g., pain, redness, swelling; 11%)
Urinary tract infection (10%)

Warnings for Kesimpta

Risk of infections
Injection reactions
Lower antibody levels
Harm to an unborn baby

Summary for Gilenya

Prescription only

Fingolimod (Gilenya) is a disease-modifying treatment option for relapsing multiple sclerosis (MS). It works well to lower the number of MS relapses. Fingolimod (Gilenya) is taken by mouth, typically once daily, and can be used by adults and children age 10 years and older. But fingolimod (Gilenya) can cause potentially serious side effects, such as a higher risk for infections and heart problems, so it's not the best choice for everyone.

Indications for Gilenya

Relapsing forms of multiple sclerosis (MS)

Pros and Cons for Gilenya

Pros

Works well in both adults and children to lower the number of MS relapses
Taken by mouth once per day
Can be used in children age 10 and older

Cons

First dose usually has to be observed for at least 6 hours
Might not be safe for pregnant or breastfeeding females
Not a good option for people with heart or liver problems

Common Side Effects for Gilenya

Headache (25%)
High liver enyzmes (15%)
Nausea (13%)
Diarrhea (13%)
Cough (12%)
Stomach pain (11%)
Influenza (11%)
Sinus inflammation (11%)
Pain in back (10%)
Pain in arms or legs (10%)

Warnings for Gilenya

Dangerously slow heart rate
Serious infections
Progressive multifocal leukoencephalopathy (PML)
Eye problems
Liver damage
Breathing problems
Harm to unborn babies
Risk of cancer
Brain problems

Prices with our coupons for Kesimpta vs. Gilenya

Kesimpta1 pen / 20mg/0.4ml

$10,789.78-

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Fingolimod1 bottle / 30 capsules of 0.5mg

$85.67$11,104.99

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Kesimpta vs. Gilenya

Kesimpta

Fingolimod

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Gilenya

Indications for Gilenya

Pros and Cons for Gilenya

Pros

Cons

Common Side Effects for Gilenya

Warnings for Gilenya

Prices with our coupons for Kesimpta vs. Gilenya

Compare other Multiple Sclerosis drugs

Browse medications by letter

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Kesimpta

Fingolimod

Summary for Kesimpta

Indications for Kesimpta

Pros and Cons for Kesimpta

Pros

Cons

Common Side Effects for Kesimpta

Warnings for Kesimpta

Summary for Gilenya

Indications for Gilenya

Pros and Cons for Gilenya

Pros

Cons

Common Side Effects for Gilenya

Warnings for Gilenya