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Compare Kesimpta vs. Gilenya

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Kesimpta (ofatumumab)
    Fingolimod (Gilenya)
  • Kesimpta (ofatumumab)
    Fingolimod (Gilenya)

  • Summary of Kesimpta vs. Gilenya

    Summary for Monoclonal antibody
    Prescription only

    Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

    Summary for Sphingosine 1-phosphate receptor modulator
    Prescription only

    Fingolimod (Gilenya) is a disease-modifying treatment option for relapsing multiple sclerosis (MS). It works well to lower the number of MS relapses. Fingolimod (Gilenya) is taken by mouth, typically once daily, and can be used by adults and children age 10 years and older. But fingolimod (Gilenya) can cause potentially serious side effects, such as a higher risk for infections and heart problems, so it's not the best choice for everyone.

  • Indications of Kesimpta vs. Gilenya

    Indications for
    •Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS
    Indications for
    •Relapsing forms of multiple sclerosis (MS)

  • Pros and Cons of Kesimpta vs. Gilenya

    Pros and Const for Monoclonal antibody
    Pros
    •Injections are once a month (after the first 3 injections)
    •Can inject at home after you're trained
    •Comes as prefilled syringes and Sensoready Pens
    •Can be kept at room temperature for up to 7 days
    Cons
    •Doesn't cure MS
    •Must give as an injection under the skin
    •Raises your risk of infections
    •Not recommended for people who are pregnant
    Pros and Const for Sphingosine 1-phosphate receptor modulator
    Pros
    •Works well in both adults and children to lower the number of MS relapses
    •Taken by mouth once per day
    •Can be used in children age 10 and older
    Cons
    •First dose usually has to be observed for at least 6 hours
    •Might not be safe for pregnant or breastfeeding females
    •Not a good option for people with heart or liver problems

  • Common Side Effects of Kesimpta vs. Gilenya

    Common Side Effects for
    •Upper respiratory tract infections (39%)
    •Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
    •Headache (13%)
    •Reaction at the injection site (e.g., pain, redness, swelling; 11%)
    •Urinary tract infection (10%)
    Common Side Effects for
    •Headache (25%)
    •High liver enyzmes (15%)
    •Nausea (13%)
    •Diarrhea (13%)
    •Cough (12%)
    •Stomach pain (11%)
    •Influenza (11%)
    •Sinus inflammation (11%)
    •Pain in back (10%)
    •Pain in arms or legs (10%)

  • Warnings of Kesimpta vs. Gilenya

    Common Side Effects for
    •Risk of infections
    •Injection reactions
    •Lower antibody levels
    •Harm to an unborn baby
    Common Side Effects for
    •Dangerously slow heart rate
    •Serious infections
    •Progressive multifocal leukoencephalopathy (PML)
    •Eye problems
    •Liver damage
    •Breathing problems
    •Harm to unborn babies
    •Risk of cancer
    •Brain problems

  • Prices with our coupons for Kesimpta vs. Gilenya

    Learn more about Kesimpta
    Learn more about Fingolimod

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