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Kesimpta vs. Copaxone

Kesimpta (ofatumumab) is an injectable medication for adults with relapsing forms of multiple sclerosis (MS). It works as a monoclonal antibody to help lessen MS flare-ups that come and go. Kesimpta (ofatumumab) is injected under the skin. You can use the Kesimpta prefilled syringes or Sensoready Pens to inject. After the first 3 weekly injections, you inject the medication once a month. Some common side effects include a higher risk of infections, pain or swelling at the injection site, and headache.

• Relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS, clinically isolated syndrome, and secondary progressive MS

• Upper respiratory tract infections (39%)
• Reactions related to the injection (e.g., fever, chills, tiredness; 21%)
• Headache (13%)
• Reaction at the injection site (e.g., pain, redness, swelling; 11%)
• Urinary tract infection (10%)

• Risk of infections
• Injection reactions
• Lower antibody levels
• Harm to an unborn baby

Glatiramer (Copaxone) is used to treat relapsing forms of multiple sclerosis (MS). Glatiramer (Copaxone) is injected under the skin, either daily or three times a week, depending on your dose. Injection sites for glatiramer (Copaxone) include the arms, stomach, hips, and thighs. It can cause common side effects such as warmth and pain at the injection site. Glatiramer (Copaxone) comes as prefilled syringes. But your provider can also write you a prescription for autoinjectors, which might be easier to use. Glatiramer is available as both brand-name and generic medications.

• Relapsing forms of multiple sclerosis (MS)

• Warmth at injection site (43%)
• Pain at injection site (40%)
• Infection (30%)
• Itching and swelling at injection site (up to 27%)
• Weakness (22%)
• General body pain (20%)
• Rash (19%)
• Nausea (15%)
• Trouble catching your breath (14%)
• Anxiety (13%)
• Chest pain (13%)
• Back pain (12%)

• Reactions after injection
• Chest pain
• Loss of fat tissue and injection site necrosis
• Liver damage