Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Zinbryta vs. Lemtrada

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Zinbryta (daclizumab) and Lemtrada (alemtuzumab) are both used to treat relapsing forms of multiple sclerosis (MS) in adults, but they have notable differences. Zinbryta is a monoclonal antibody that helped lower inflammationin the brain. However, it was discontinued in the United States due to safety concerns, including liver injury and immune-related problems. In contrast, Lemtrada, an anti-CD52 monoclonal antibody, is still available but only for those who haven't responded well to at least two other MS medications. Lemtrada is administered as an annual IV infusion, after the first treatment course. It has a high risk of serious side effects, such as developing autoimmune problems, infections, and cancer, and is only available through a special REMS program.

  • Zinbryta (daclizumab)
    Lemtrada (alemtuzumab)
  • Zinbryta (daclizumab)
    Lemtrada (alemtuzumab)

  • Summary of Zinbryta vs. Lemtrada

    Summary for Monoclonal antibody

    Zinbryta (daclizumab) is a medication used to treat relapsing forms of multiple sclerosis (MS) in adults. It's no longer available in the United States, because it was discontinued.

    Summary for Anti-CD52 monoclonal antibody
    Prescription only

    Lemtrada (alemtuzumab) is an anti-CD52 monoclonal antibody. It's used to treat relapsing forms of multiple sclerosis (MS) in adults, but only when other MS medications haven't worked well. Lemtrada (alemtuzumab) is given as an infusion through the veins once per year by a healthcare provider. Since this medication has many risks and side effects, it's only available through a Risk Evaluation and Mitigation Strategy (REMS) program) called the Lemtrada REMS program. Some common side effects of Lemtrada (alemtuzumab) include rash, headache, and fever.

  • Indications of Zinbryta vs. Lemtrada

    Indications for
    •Relapsing forms of multiple sclerosis (MS)
    Indications for
    •Relapsing forms of multiple sclerosis (MS) in adults who haven't responded well enough to at least two other MS medications

  • Pros and Cons of Zinbryta vs. Lemtrada

    Pros and Const for Monoclonal antibody
    Pros
    Cons
    Pros and Const for Anti-CD52 monoclonal antibody
    Pros
    •Works well to treat relapsing forms of MS
    •Treatment courses are short and are only once per year
    •Not many known interactions with other medications
    Cons
    •A lot of potential risks and side effects, including serious allergic reaction, blood problems, and liver problems
    •Each treatment will take a least 6 hours at the clinic because of pre-treatment, infusion time, and monitoring time
    •Needs to be given as an IV injection by a healthcare professional

  • Common Side Effects of Zinbryta vs. Lemtrada

    Common Side Effects for
    Common Side Effects for
    •Rash (53%)
    •Headache (52%)
    •Fever (29%)
    •Sore throat, runny nose (25%)
    •Nausea (21%)
    •Urinary tract infection (19%)
    •Tiredness (18%)
    •Difficulty sleeping (16%)
    •Upper respiratory tract infection (16%)
    •Herpes viral infection (16%)
    •Hives (16%)

  • Warnings of Zinbryta vs. Lemtrada

    Common Side Effects for
    Common Side Effects for
    •Lemtrada REMS program
    •Autoimmune problems
    •Severe allergy and infusion reactions
    •Stroke
    •Risk of cancers
    •Inflammatory problems
    •Serious infections

  • Prices with our coupons for Zinbryta vs. Lemtrada

    Learn more about Zinbryta
    Learn more about Lemtrada

Compare other Multiple Sclerosis drugs

Zinbryta vs LemtradaZinbryta vs TecfideraZinbryta vs TysabriEntyvio vs OrtikosMavenclad vs RebifMayzent vs ExtaviaMayzent vs GlatopaMayzent vs LemtradaMayzent vs PlegridyMayzent vs RebifMayzent vs TysabriOrencia vs RituxanOrtikos vs AzasanOrtikos vs ImuranOrtikos vs RemicadeOrtikos vs StelaraOrtikos vs TrexallOrtikos vs TysabriPlegridy vs TecfideraRebif vs LemtradaRebif vs TecfideraRebif vs TysabriRituxan vs ActemraRituxan vs CytoxanRituxan vs LeukeranRituxan vs RemicadeRituxan vs TysabriVumerity vs MayzentVumerity vs TysabriZeposia vs Rebif
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.