Why was Zinbryta (daclizumab) discontinued?

Zinbryta (daclizumab) was discontinued due to concerns of [having more safety risks with taking the medication than its benefits](https://www.fda.gov/drugs/drug-safety-and-availability/fda-working-manufacturers-withdraw-zinbryta-market-united-states). Some of these safety risks included liver injury and other immune-related problems.

What other medications can I use in place of Zinbryta (daclizumab)?

While Zinbryta (daclizumab) has been discontinued, there are still several [other medications available for the treatment of MS](https://www.nationalmssociety.org/Treating-MS/Medications). Examples include [glatiramer (Copaxone)](https://www.goodrx.com/glatiramer/what-is), [Kesimpta (ofatumumab)](https://www.goodrx.com/kesimpta/what-is), and [Gilenya (fingolimod)](https://www.goodrx.com/gilenya/what-is). Your provider will help guide you to the best treatment option for your MS.

Zinbryta

Q: What is Zinbryta (daclizumab)?

Zinbryta (daclizumab) is a [monoclonal antibody](https://www.goodrx.com/classes/monoclonal-antibodies) used to treat relapsing forms of MS. It's not exactly known how it works, but it's thought to work by [turning off certain proteins and processes](https://link.springer.com/article/10.1007/s13311-017-0553-8) in your brain to lower [inflammation](https://www.goodrx.com/health-topic/autoimmune/what-is-inflammation) and treat symptoms of MS.

daclizumab

Used for Multiple Sclerosis

Basics FAQs Dosage Alternatives Prices Medicare

Zinbryta (daclizumab) is a medication used to treat relapsing forms of multiple sclerosis (MS) in adults. It's no longer available in the United States, because it was discontinued.

Reviewed by:

Robert Chad Hakim, PharmD, BCCCP

Kristianne Hannemann, PharmD

Last reviewed on July 12, 2022

Basics FAQs Dosage Alternatives Prices Medicare

What is Zinbryta (daclizumab)?

What is Zinbryta (daclizumab) used for?

Relapsing forms of multiple sclerosis (MS)

Drug facts

Common BrandsZinbryta(brand no longer available)

Drug ClassMonoclonal antibody

Controlled Substance ClassificationNot a controlled medication

Generic StatusNo lower-cost generic available

AvailabilityDiscontinued

Common questions about Zinbryta (daclizumab)

Zinbryta (daclizumab) is a monoclonal antibody used to treat relapsing forms of MS. It's not exactly known how it works, but it's thought to work by turning off certain proteins and processes in your brain to lower inflammation and treat symptoms of MS.

No, Zinbryta (daclizumab) has been discontinued and is no longer available in the United States.

Zinbryta (daclizumab) was discontinued due to concerns of having more safety risks with taking the medication than its benefits. Some of these safety risks included liver injury and other immune-related problems.

While Zinbryta (daclizumab) has been discontinued, there are still several other medications available for the treatment of MS. Examples include glatiramer (Copaxone), Kesimpta (ofatumumab), and Gilenya (fingolimod). Your provider will help guide you to the best treatment option for your MS.