Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Bimzelx vs. Tremfya

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bimzelx (bimekizumab) and Tremfya (guselkumab) are both injectable medications used to treat moderate-to-severe plaque psoriasis, psoriatic arthritis, and other conditions. They are both monoclonal antibodies, but they work differently. Bimzelx is an interleukin antagonist that blocks interleukin-17A (IL-17A) and interleukin-17F (IL-17F), while Tremfya targets interleukin-23 (IL-23). Tremfya is also approved for treating ulcerative colitis and Crohn's disease, whereas Bimzelx is approved for treating non-radiographic axial spondyloarthritis, ankylosing spondylitis, and hidradenitis suppurativa. Bimzelx is typically injected every month at first, then every other month, while Tremfya is injected once at the start, again at week 4, and then every 8 weeks. Bimzelx is available as prefilled autoinjectors and syringes, whereas Tremfya offers a prefilled syringe or a patient-controlled injector. Both medications can cause injection site reactions and increase the risk of infections. Both should be used with caution if you have a history of infections or liver issues.

  • Bimzelx (bimekizumab)
    Tremfya (guselkumab)
  • Bimzelx (bimekizumab)
    Tremfya (guselkumab)

  • Summary of Bimzelx vs. Tremfya

    Summary for Interleukin antagonist
    Prescription only

    Bimzelx (bimekizumab or bimekizumab-bkzx) is an injection that's used to treat several inflammatory conditions in adults. They include plaque psoriasis, psoriatic arthritis, and hidradenitis suppurativa, to name a few. It's a type of monoclonal antibody called an interleukin antagonist. It works to reduce inflammation in the body. Bimzelx (bimekizumab) comes in prefilled autoinjectors or prefilled syringes. You inject the medication under the skin either every month or every other month. It can cause side effects like upper respiratory infections.

    Summary for Interleukin antagonist
    Prescription only

    Tremfya (guselkumab) is an injection for adults with certain inflammatory conditions. It helps treat plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Tremfya (guselkumab) is a monoclonal antibody known as an interleukin antagonist. It calms your immune system to lower inflammation. The dosing schedule is every 1 or 2 months, depending on your condition and how far along you are in treatment. Side effects are upper respiratory infections, headache, and injection site reactions. There's also a risk of other infections and liver problems as long-term side effects.

  • Indications of Bimzelx vs. Tremfya

    Indications for
    •Moderate-to-severe plaque psoriasis
    •Psoriatic arthritis
    •Non-radiographic axial spondyloarthritis
    •Ankylosing spondylitis
    •Moderate-to-severe hidradenitis suppurativa
    Indications for
    •Moderate-to-severe plaque psoriasis
    •Active psoriatic arthritis
    •Moderate-to-severe ulcerative colitis (UC)
    •Moderate-to-severe Crohn's disease (CD)

  • Pros and Cons of Bimzelx vs. Tremfya

    Pros and Const for Interleukin antagonist
    Pros
    •Dosing schedule is either every month or every other month, so it's convenient for most people
    •An option for plaque psoriasis if topical medications have stopped working
    •Available as prefilled autoinjectors and prefilled syringes
    Cons
    •Can cause injection reactions, such as pain, bruising, and swelling
    •Might raise the risk of infections
    •Unknown if safe during pregnancy or while breastfeeding
    Pros and Const for Interleukin antagonist
    Pros
    •An option for adults with plaque psoriasis who've already tried topical treatment
    •Given every 1 or 2 months (depending on your condition and treatment plan)
    •Few side effects
    •Can give yourself injections under the skin at home after you get trained
    Cons
    •Given as an injection under the skin or injection through the vein
    •Raises the risk of infections
    •Can cause some injection site reactions
    •Can take several months to see the benefits of the medication

  • Common Side Effects of Bimzelx vs. Tremfya

    Common Side Effects for
    •Upper respiratory tract infection (runny nose, sore throat; 15%)
    •Oral thrush (9%)
    •Headache (3%)
    •Injection site reactions (redness, pain, swelling, bruising; 3%)
    •Fungal skin infections (3%)
    Common Side Effects for
    •Upper respiratory infections (14%)
    •Headache (5%)
    •Injection site reactions (5%)
    •Joint pain (3%)

  • Warnings of Bimzelx vs. Tremfya

    Common Side Effects for
    •Suicidal thoughts or behavior
    •Risk of infections
    •Liver problems
    •Inflammatory bowel disease
    •Interaction with vaccines
    Common Side Effects for
    •Serious allergic reactions
    •Risk of infections
    •Liver damage
    •Interaction with vaccines

  • Prices with our coupons for Bimzelx vs. Tremfya

    Learn more about Bimzelx
    Learn more about Tremfya

Compare other Plaque Psoriasis drugs

Bimzelx vs CosentyxBimzelx vs TremfyaSkyrizi vs BimzelxTaltz vs BimzelxCosentyx vs TremfyaDuobrii vs SkyriziDuobrii vs TremfyaEntyvio vs SkyriziOmvoh vs SkyriziRinvoq vs SkyriziSkyrizi vs CosentyxSkyrizi vs DupixentSkyrizi vs EnbrelSkyrizi vs HumiraSkyrizi vs IlumyaSkyrizi vs OtezlaSkyrizi vs RemicadeSkyrizi vs SimponiSkyrizi vs TaltzSotyktu vs SkyriziStelara vs SkyriziTremfya vs CosentyxTremfya vs DupixentTremfya vs EntyvioTremfya vs HumiraTremfya vs IlumyaTremfya vs OtezlaTremfya vs SkyriziTremfya vs StelaraTremfya vs Taltz
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.