Corticosteroid-retinoid combinations are used to treat skin conditions like plaque psoriasis. These medications work by combining the anti-inflammatory effects of corticosteroids with the properties of retinoids, helping to reduce redness, swelling, and the overproduction of skin cells. These treatments are typically available in topical forms, such as lotions. One example is Duobrii (halobetasol propionate / tazarotene).