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Compare Nucala vs. Fasenra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Nucala (mepolizumab)
    Fasenra (benralizumab)
  • Nucala (mepolizumab)
    Fasenra (benralizumab)

  • Summary of Nucala vs. Fasenra

    Summary for Interleukin antagonist
    Prescription only

    Nucala (mepolizumab) is an injection that treats certain inflammatory problems. This includes severe asthma in people 6 years and older. It can also treat chronic obstructive pulmonary disease (COPD) and sinus congestion with nasal polyps in adults. The medication works as an interleukin antagonist to lower inflammation. It's injected under the skin once a month. You can inject it on your own with the prefilled autoinjector or syringe. A healthcare professional can also give the injection at a medical office. Side effects include headache and injection site reactions.

    Summary for Interleukin antagonist
    Prescription only

    Fasenra (benralizumab) is an injectable biologic medication that's used to treat severe eosinophilic asthma in people 6 years and older. It belongs to a class of medications called interleukin antagonists. Fasenra (benralizumab) is available as a pen that you can inject at home, either by yourself or with the help of a caregiver. The usual dosing is to inject under the skin every month for the first 3 months, and then every 2 months after that. Common side effects include headache and sore throat.

  • Indications of Nucala vs. Fasenra

    Indications for
    •Severe asthma - add-on maintenance for people ages 6 years and older
    •Chronic obstructive pulmonary disease (COPD) - add-on maintenance for adults
    •Chronic rhinosinusitis with nasal polyps - add-on maintenance for adults
    •Eosinophilic granulomatosis with polyangiitis (EGPA) - for adults
    •Hypereosinophilic syndrome (HES) - for people ages 12 years and older
    Indications for
    •Add-on treatment for severe eosinophilic asthma in people 6 years and older

  • Pros and Cons of Nucala vs. Fasenra

    Pros and Const for Interleukin antagonist
    Pros
    •Only given once a month
    •Available as a prefilled autoinjector and syringe for injections at home
    Cons
    •Must give as an injection
    •Doses higher than 100 mg need more than one injection given one after another
    Pros and Const for Interleukin antagonist
    Pros
    •Maintenance dose is injected every 2 months
    •Shown to lower the rate of asthma attacks
    •Available as a pre-filled pen so you can inject conveniently at home
    Cons
    •Can't treat asthma attacks
    •Needs to be injected, which can be inconvenient compared to pills or an inhaler
    •Not approved for children under 6 years old

  • Common Side Effects of Nucala vs. Fasenra

    Common Side Effects for
    •Headache (19%)
    •Injection site reactions (e.g., pain, redness, swelling, itching, burning; 8%)
    •Back pain (5%)
    •Fatigue (5%)
    Common Side Effects for
    •Headache (8%)
    •Sore throat (5%)
    •Fever (3%)

  • Warnings of Nucala vs. Fasenra

    Common Side Effects for
    •Allergic reactions
    •Not for an asthma or COPD attack
    •Caution when using corticosteroids
    •Possible herpes zoster infection (shingles)
    •Unclear effect in people with parasitic worm infections
    Common Side Effects for
    •Serious allergic reactions
    •Not for asthma attacks
    •Suddenly stopping corticosteroids
    •Parasitic worm infection care

  • Prices with our coupons for Nucala vs. Fasenra

    Learn more about Nucala
    Learn more about Fasenra

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