Compare Singular vs. Claritin

Montelukast (Singulair) and loratadine (Claritin) are both used to treat allergies, but they work in different ways and are used for different purposes. Montelukast is a leukotriene receptor antagonist that helps manage asthma and prevent exercise-induced asthma, in addition to treating seasonal and year-round allergies. It is available only by prescription and comes in various forms, including tablets, chewable tablets, and oral granules. Montelukast is not suitable for immediate relief of asthma attacks. Loratadine, on the other hand, is an over-the-counter antihistamine that primarily provides short-term relief for allergy symptoms like runny nose and itchy eyes. It is available in tablets, chewable tablets, and oral solutions. Loratadine is not recommended for children under 2 years old without a healthcare provider's advice. Montelukast is taken once daily, usually in the evening for asthma, while loratadine is also taken once daily but can be taken at any time. Montelukast may cause serious mental health side effects, whereas loratadine heachache and dry mouth. Loratadine is less likely to cause drowsiness compared to other antihistamines but can still make you sleepy.