Compare Singulair vs. Allegra

Montelukast (Singulair) and fexofenadine (Allegra) are both used to treat allergy symptoms, but they work in different ways and are used for different conditions. Montelukast is a leukotriene receptor antagonist that helps with long-term asthma management and exercise-induced asthma, in addition to treating seasonal and year-round allergies. It is available only by prescription and comes in various forms, including tablets, chewable tablets, and granules. On the other hand, fexofenadine is an over-the-counter antihistamine that provides short-term relief for allergy symptoms and hives. It is available in tablets, fast-melting tablets, and liquids. Montelukast is typically taken once daily, while fexofenadine can be taken once or twice a day, depending on the formulation. Montelukast has a risk of serious mental health side effects, whereas fexofenadine can cause headaches and dry mouth. Fexofenadine is less likely to cause drowsiness compared to other antihistamines.