Key takeaways
Breo Ellipta (fluticasone/vilanterol) and Advair (fluticasone/salmeterol) are both combination inhalers used for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). They belong to the same medication class, combining an inhaled corticosteroid (ICS) with a long-acting beta agonist (LABA). However, there are several differences between them. Breo Ellipta is typically taken once daily, while Advair is taken twice daily. Breo Ellipta is available in three strengths, but its generic form is available in only two strengths. Advair comes in two forms: Advair Diskus and Advair HFA, with different strengths for each. Both medications are available as a lower-cost generic. Common side effects for both medications include upper respiratory tract infections and headaches, but Advair users may also experience sore throat and nausea more frequently.
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