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Compare Incruse Ellipta vs. Breo Ellipta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Incruse Ellipta (umeclidinium) and Breo Ellipta (fluticasone/vilanterol) are both inhalers used for the maintenance treatment of chronic obstructive pulmonary disease (COPD), but they have some key differences. Incruse Ellipta is a long-acting muscarinic antagonist (LAMA) that works by relaxing the muscles in your airways. Breo Ellipta, on the other hand, combines an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) to reduce inflammation and relax airway muscles. Incruse Ellipta is only available as a brand-name medication, whereas Breo Ellipta has a lower-cost generic option. Incruse Ellipta is not approved for asthma, but Breo Ellipta is approved for both COPD and asthma in adults and children. Common side effects of Incruse Ellipta include cold symptoms and cough, while Breo Ellipta can cause upper respiratory infections, sore throat, and headache. Additionally, Breo Ellipta requires you to rinse your mouth after use to prevent fungal infections, a step not needed with Incruse Ellipta.

  • Incruse ellipta (umeclidinium)
    Breo ellipta (fluticasone / vilanterol)
  • Incruse ellipta (umeclidinium)
    Breo ellipta (fluticasone / vilanterol)

  • Summary of Incruse Ellipta vs. Breo Ellipta

    Summary for LAMA
    Prescription only

    Incruse Ellipta (umeclidinium) is an long-acting muscarinic antagonist (LAMA). It's an inhaler used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. Incruse Ellipta (umeclidinium) is inhaled through the mouth once per day. People who use Incruse Ellipta (umeclidinium) typically don't experience too many side effects, but ones reported include common cold symptoms, like sore throat and cough.

    Summary for ICS / LABA combo
    Prescription only

    Breo is a combination inhaler used for maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children. It contains two active ingredients, fluticasone (an inhaled corticosteroid, or ICS) and vilanterol (a long-acting beta agonist, or LABA). Breo Ellipta (fluticasone / vilanterol) is inhaled through the mouth once per day. It's available as a lower-cost generic. Side effects can differ based on your age and your Breo Ellipta (fluticasone / vilanterol) dose, but generally include upper respiratory tract infections, sore throat, and headache.

  • Indications of Incruse Ellipta vs. Breo Ellipta

    Indications for
    •Maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults
    Indications for
    •Maintenance treatment of asthma
    •Maintenance treatment of COPD

  • Pros and Cons of Incruse Ellipta vs. Breo Ellipta

    Pros and Const for LAMA
    Pros
    •Inhaled once per day
    •Might be easier to use compared to some other dry powder inhalers
    •Can be stored at room temperature
    Cons
    •Can't use if you're severely allergic to milk proteins because it contains lactose
    •Not a rescue inhaler for sudden breathing problems
    •Brand-name medication only
    Pros and Const for ICS / LABA combo
    Pros
    •Long-term control of asthma and COPD symptoms
    •Inhaled only once per day, unlike other similar inhalers which are used twice per day
    •Might be easier to use compared to some other dry powder inhalers
    Cons
    •Can't use if you're severely allergic to milk proteins because it contains lactose
    •Need to rinse your mouth with water after each use to prevent fungal infections (thrush) in your mouth and throat
    •Doesn't replace your rescue inhaler

  • Common Side Effects of Incruse Ellipta vs. Breo Ellipta

    Common Side Effects for
    •Common cold (8%)
    •Upper respiratory tract infection (5%)
    •Cough (3%)
    •Joint pain (2%)
    Common Side Effects for

    COPD:

    •Common cold (9%)
    •Upper respiratory tract infection (7%)
    •Headache (7%)
    •Oral thrush (fungal infection in mouth) (5%)

    Asthma (adults):

    •Headache (8%)
    •Common cold (7%)

    Asthma (children):

    •Common cold (10%)
    •Upper respiratory tract infection (7%)

  • Warnings of Incruse Ellipta vs. Breo Ellipta

    Common Side Effects for
    •Not a rescue inhaler
    •Narrowing of your airways (bronchospasm)
    •Serious allergic reactions
    •Worsening narrow-angle glaucoma
    •Trouble urinating
    Common Side Effects for
    •Not for asthma attacks, COPD flare ups, or worsening breathing
    •Fungal infection in the mouth
    •Narrowing of your airways (bronchospasm)
    •Higher risk of infections
    •Changes in stress hormone levels
    •Delayed growth in children
    •Eye and vision problems
    •Heart problems
    •Low potassium levels in the blood
    •Allergic reactions

  • Prices with our coupons for Incruse Ellipta vs. Breo Ellipta

    Learn more about Incruse ellipta
    Learn more about Breo ellipta

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