Compare Anoro Ellipta vs. Trelegy Ellipta

Anoro Ellipta (umeclidinium/vilanterol) and Trelegy Ellipta (fluticasone/umeclidinium/vilanterol) are both inhalers used to manage chronic obstructive pulmonary disease (COPD), but they have some key differences. Anoro Ellipta combines a long-acting muscarinic antagonist (LAMA) and a long-acting beta-agonist (LABA) to help you breathe easier, while Trelegy Ellipta adds an inhaled corticosteroid (ICS) to the mix, which helps reduce inflammation in your lungs. Trelegy Ellipta is also approved for treating asthma, unlike Anoro Ellipta. You don't need to rinse your mouth after using Anoro Ellipta, but you must do so with Trelegy Ellipta to prevent oral thrush. Both medications are taken once daily, but neither has a generic version, making them potentially expensive. Additionally, Anoro Ellipta contains milk protein, which can cause severe allergies in some people, a concern also present with Trelegy Ellipta.