Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Breztri vs. Anoro Ellipta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Breztri Aerosphere (budesonide/glycopyrrolate/formoterol) and Anoro Ellipta (umeclidinium/vilanterol) are both inhaled medications used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. However, they differ in several ways. Breztri Aerosphere is a combination of three medications: an inhaled corticosteroid (ICS), a long-acting muscarinic antagonist (LAMA), and a long-acting beta agonist (LABA). In contrast, Anoro Ellipta combines only a LAMA and a LABA, and it does not contain a steroid. Breztri is taken as two inhalations twice daily, while Anoro Ellipta is taken as one inhalation once daily. Both medications are only available as brand-name medications. Common side effects of both medications include upper respiratory tract infections and pneumonia and should not be used for sudden breathing problems. You should have a rescue inhaler like albuterol on hand for such situations. Additionally, Breztri requires rinsing your mouth after use to prevent oral thrush, a step not needed with Anoro Ellipta.

  • Breztri
    Anoro ellipta (umeclidinium / vilanterol)
  • Breztri
    Anoro ellipta (umeclidinium / vilanterol)

  • Summary of Breztri vs. Anoro Ellipta

    Summary for ICS / LAMA / LABA
    Prescription only

    Breztri Aerosphere is a combination inhaler that contains budesonide (an inhaled corticosteroid), glycopyrrolate (a long-acting muscarinic antagonist), and formoterol (a long-acting beta agonist). It's used for maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. Breztri is inhaled through the mouth and into the lungs twice per day every day. The most common side effects are upper respiratory tract infections and pneumonia. Breztri is brand name only and not available as a lower-cost generic.

    Summary for LAMA / LABA combo
    Prescription only

    Anoro Ellipta is a steroid-free inhaler that contains umeclidinium (a long-acting muscarinic antagonist, or LAMA) and vilanterol (a long-acting beta agonist, or LABA). It's FDA-approved for maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. This Ellipta inhaler is inhaled through the mouth once per day. Side effects aren't common, but some people have reported sore throat and diarrhea.

  • Indications of Breztri vs. Anoro Ellipta

    Indications for
    •Maintenance treatment of chronic obstructive pulmonary disease (COPD)
    Indications for
    •Maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults

  • Pros and Cons of Breztri vs. Anoro Ellipta

    Pros and Const for ICS / LAMA / LABA
    Pros
    •Lowers the risk of COPD flare-ups
    •Combination of three medications in a single inhaler
    •Can be used with a spacer to make it easier to take a dose
    Cons
    •Need to rinse your mouth after each dose
    •Need to inhale 2 puffs twice daily
    •Doesn't treat sudden worsening symptoms of COPD
    Pros and Const for LAMA / LABA combo
    Pros
    •Combination of two bronchodilators within a single inhaler
    •Inhaled once per day
    •No need to rinse your mouth after a dose since it doesn't contain a steroid
    Cons
    •Doesn't replace your rescue inhaler for sudden trouble breathing
    •Can't use if you're severely allergic to milk proteins because it contains lactose
    •Might not be a good choice for people who've trouble urinating

  • Common Side Effects of Breztri vs. Anoro Ellipta

    Common Side Effects for
    •Upper respiratory tract infection (6%)
    •Pneumonia (5%)
    Common Side Effects for
    •Sore throat (2%)
    •Diarrhea (2%)

  • Warnings of Breztri vs. Anoro Ellipta

    Common Side Effects for
    •Not for asthma, COPD flare ups, or worsening breathing
    •Fungal infection in the mouth
    •Narrowing of your airways (bronchospasm)
    •Allergic reactions
    •Higher risk of infections
    •Changes in stress hormone levels
    •Eye and vision problems
    •Heart problems
    •Low potassium levels in the blood
    •Trouble urinating
    Common Side Effects for
    •Not for COPD flare ups or worsening breathing
    •Narrowing of your airways (bronchospasm)
    •Serious allergic reactions
    •Worsening narrow-angle glaucoma
    •Trouble urinating
    •Heart problems
    •Low potassium level in the blood

  • Prices with our coupons for Breztri vs. Anoro Ellipta

    Learn more about Breztri
    Learn more about Anoro ellipta

Compare other COPD drugs

Breztri Aerosphere vs AdvairBreztri Aerosphere vs AlbuterolBreztri Aerosphere vs Anoro ElliptaBreztri Aerosphere vs SpirivaBreztri Aerosphere vs SymbicortBreztri Aerosphere vs Trelegy ElliptaAdvair vs AlbuterolAdvair vs PulmicortAdvair vs Trelegy ElliptaAirduo vs AdvairAnoro Ellipta vs SymbicortAnoro Ellipta vs Trelegy ElliptaBreo Ellipta vs SymbicortBreo Ellipta vs Trelegy ElliptaCombivent vs SymbicortDulera vs SymbicortDupixent vs SymbicortFlovent vs SymbicortIncruse Ellipta vs SymbicortIncruse Ellipta vs Trelegy ElliptaIpratropium vs SpirivaQvar vs SymbicortSingulair vs SymbicortSpiriva vs AdvairSpiriva vs AlbuterolSpiriva vs Spiriva RespimatSpiriva vs SymbicortSpiriva vs XopenexSymbicort vs AdvairSymbicort vs Albuterol
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.