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Compare Wixela Inhub vs. Advair

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Wixela Inhub (fluticasone/salmeterol) and Advair (fluticasone/salmeterol) are both prescription combination inhalers used for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). They both contain an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA). However, there are some differences between them. Wixela Inhub is the generic version of Advair Diskus and is available in three strengths: 100 mcg/50 mcg, 250 mcg/50 mcg, and 500 mcg/50 mcg. Advair is available as Advair Diskus and Advair HFA. Advair Diskus form is available in the same three strengths, while the HFA form comes as 45 mcg/21 mcg, 115 mcg/21 mcg, and 230 mcg/21 mcg. Wixela Inhub and Advair Diskus are typically taken as one inhalation twice daily, but Advair HFA requires two puffs twice daily. Common side effects for both include upper respiratory infections, sore throat, and headaches, but Advair HFA users may also experience muscle and bone pain. Both medications can cause oral thrush (a fungal infection), so it's important to rinse your mouth after use.

  • Wixela inhub (fluticasone / salmeterol)
    Advair (fluticasone / salmeterol)
  • Wixela inhub (fluticasone / salmeterol)
    Advair (fluticasone / salmeterol)

  • Summary of Wixela Inhub vs. Advair

    Summary for ICS / LABA combo
    Prescription only

    Wixela Inhub is a combination inhaler that contains fluticasone (an inhaled corticosteroid) and salmeterol (a long-acting beta agonist, or LABA). This medication is used as maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children. It's inhaled by mouth twice daily. Some of the more common side effects of Wixela Inhub (fluticasone / salmeterol) include upper respiratory tract infections, sore throat, and headaches. Wixela Inhub is the generic version of Advair Diskus.

    Summary for ICS / LABA combo
    Prescription only

    Advair is a combination inhaler that contains fluticasone (an inhaled corticosteroid) and salmeterol (a long-acting beta agonist, or LABA). Advair Diskus is used for maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children, where as Advair HFA is for asthma only. Advair (fluticasone / salmeterol) is inhaled through the mouth, typically 1 to 2 puffs twice daily. Some common side effects of this medication include upper respiratory tract infection, sore throat, and headache.

  • Indications of Wixela Inhub vs. Advair

    Indications for
    •Maintenance treatment of asthma
    •Maintenance treatment of COPD - Wixela Inhub 250/50 only
    Indications for
    •Maintenance treatment of asthma
    •Maintenance treatment of COPD - Advair Diskus 250/50 only

  • Pros and Cons of Wixela Inhub vs. Advair

    Pros and Const for ICS / LABA combo
    Pros
    •Works well to lower the risk of asthma or COPD symptoms
    •Combines two medications into a single inhaler for convenience
    •Can be used in children as young as 4 years old with asthma
    Cons
    •Not a rescue inhaler for treating sudden trouble breathing
    •Needs to be used twice per day
    •Can cause fungal infections (thrush) in your mouth and throat
    •Not a good choice for people allergic to lactose
    Pros and Const for ICS / LABA combo
    Pros
    •Works well to lower the risk of asthma or COPD symptoms
    •Combines two medications into a single inhaler for convenience
    •Available as two different types of inhalers (Advair Diskus and Advair HFA)
    Cons
    •Can cause fungal infections (thrush) in your mouth and throat
    •Advair Diskus contains lactose, so it might not be safe for people with severe milk protein allergies
    •Doesn't replace your rescue inhaler

  • Common Side Effects of Wixela Inhub vs. Advair

    Common Side Effects for
    •Upper respiratory infection (up to 27%)
    •Sore throat (up to 13%)
    •Headache (up to 13%)
    •Bronchitis (up to 8%)
    •Cough (up to 6%)
    •Nausea and vomiting (up to 6%)
    •Hoarseness and changes in voice (up to 5%)
    •Sinus infection (up to 5%)
    Common Side Effects for

    Advair Diskus:

    •Upper respiratory infection (up to 27%)
    •Sore throat (up to 13%)
    •Headache (up to 13%)
    •Bronchitis (up to 8%)
    •Cough (up to 6%)
    •Nausea and vomiting (up to 6%)
    •Hoarseness (up to 5%)

    Advair HFA:

    •Upper respiratory infection (up to 24%)
    •Headache (up to 21%)
    •Throat irritation (up to 9%)
    •Muscle and bone pain (up to 7%)
    •Nausea and vomiting (up to 5%)

  • Warnings of Wixela Inhub vs. Advair

    Common Side Effects for
    •Not for use in asthma attack or for worsening breathing
    •Fungal infection in the mouth
    •Narrowing of your airways (bronchospasm)
    •Higher risk of infections
    •Altered stress hormone levels
    •Delayed growth in children
    •Eye and vision problems
    •Heart problems
    •Low potassium levels in the blood
    •Allergic reactions
    Common Side Effects for
    •Not for use in asthma attack or for worsening breathing
    •Fungal infection in the mouth
    •Narrowing of your airways (bronchospasm)
    •Higher risk of infections
    •Altered stress hormone levels
    •Delayed growth in children
    •Eye and vision problems
    •Heart problems
    •Low potassium levels in the blood
    •Allergic reactions

  • Prices with our coupons for Wixela Inhub vs. Advair

    Learn more about Wixela inhub
    Learn more about Advair

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