Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Montelukast (Singulair) and Flovent (fluticasone) are both used to manage asthma, but they work in different ways and have different uses. Montelukast is a leukotriene receptor antagonist taken orally, while Flovent is an inhaled corticosteroid. Montelukast is used for long-term asthma treatment, exercise-induced asthma prevention, and year-round or seasonal allergies management. It is taken once daily. In contrast, Flovent is used specifically for the maintenance treatment of asthma and must be inhaled twice daily. Montelukast is available in various forms, including tablets, chewable tablets, and granules, making it suitable for children and those who have trouble with inhalers. Flovent, on the other hand, comes in two types of inhalers: HFA and Diskus. Both montelukast and Flovent are not suitable for treating sudden asthma attacks. Flovent requires you to rinse your mouth after each use to prevent fungal infections, a step not needed with montelukast. Additionally, montelukast has a risk of serious mental health side effects, whereas Flovent can cause throat irritation and potential growth delays in children.
Montelukast (Singular)
Flovent (fluticasone)
Montelukast (Singular)
Flovent (fluticasone)
Summary of Singular vs. Flovent
Summary for Leukotriene receptor antagonist
Prescription only
Montelukast, the generic for Singulair, is used to help control asthma over time and prevent breathing problems during exercise in both adults and children. It's also used to help relieve allergy symptoms. Montelukast (Singular) comes as tablets, chewable tablets, or oral granules and is usually taken by mouth once a day. Common side effects include upper respiratory infection and headache, and it has a boxed warning for serious mood and behavior changes.
Summary for Inhaled corticosteroid (ICS)
Prescription only
Flovent (fluticasone) is an inhaled corticosteroid medication used in people 4 years and older with asthma. It helps keep lung inflammation low and the airways open. This inhaler is used twice per day. When used every day, Flovent (fluticasone) can lower the number and severity of asthma attacks. It's not a rescue inhaler, so it won't help an asthma attack that has already started.
Indications of Singular vs. Flovent
Indications for
•Long-term treatment of asthma - age 12 months and older